Antioxidant activity of aquilaria malaccensis (thymelaeaceae) leaves

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Abstract
Pharmacognosy Research,2009,1,5,270-273.
DOI:
Published:January 2010
Type:Original Article
Authors:
Author(s) affiliations:

Huda A.W.N.*1, Munira M.A.S.1, Fitrya S.D.2 & Salmah M.3

1Department of Chemical Sciences, Faculty of Science & Technology, Universiti Malaysia Terengganu, MALAYSIA

2Institute of Marine Biotechnology, Universiti of Malaysia Terengganu, MALAYSIA 3Malaysian Nuclear Agency (MNA), Kajang, Selangor, MALAYSIA

Abstract:

The phytochemical and antioxidant activity of Aquilaria malaccensis leaves were investigated. The sequential maceration extraction methods utilizing solvents with different polarities namely hexane, ethyl acetate and methanol yielded the corresponding crude extract. The extracts were subjected to preliminary phytochemical screening and revealed the presence of alkaloids, flavanoids, triterpenoids, steroids and saponins. The phytochemical screening suggests that flavanoids present in this species might provide a great value of antioxidant activity. Preliminary screenings of the free radical scavenging activity on the extracts of the plants with 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) were tested and showed positive result. Quarcetine was used as reference standard. The extracts exhibited strong antioxidant activity radical scavenging activity with IC50 value of 8.0 × 102 μg/ml, 1.6 × 102 μg/ml, 1.4 × 102 μg/ml, 30.0 μg/ml and 3.33 μg/ ml for hexane, DCM, ethyl acetate, methanol and quarcetine respectively.

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Percentage of inhibition H-donor activity of Quercetin as measured using DPPH assay with different concentration

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