01686nas a2200205 4500008004100000245007300041210006900114260001800183300001200201490000600213520107900219653002501298653002601323653001501349100001601364700001801380700001601398700001401414856005201428 2009 eng d00aAntioxidant activity of aquilaria malaccensis (thymelaeaceae) leaves0 aAntioxidant activity of aquilaria malaccensis thymelaeaceae leav cJanuary 2010 a270-2730 v13 a
The phytochemical and antioxidant activity of Aquilaria malaccensis leaves were investigated. The sequential maceration extraction methods utilizing solvents with different polarities namely hexane, ethyl acetate and methanol yielded the corresponding crude extract. The extracts were subjected to preliminary phytochemical screening and revealed the presence of alkaloids, flavanoids, triterpenoids, steroids and saponins. The phytochemical screening suggests that flavanoids present in this species might provide a great value of antioxidant activity. Preliminary screenings of the free radical scavenging activity on the extracts of the plants with 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) were tested and showed positive result. Quarcetine was used as reference standard. The extracts exhibited strong antioxidant activity radical scavenging activity with IC50 value of 8.0 × 102 μg/ml, 1.6 × 102 μg/ml, 1.4 × 102 μg/ml, 30.0 μg/ml and 3.33 μg/ ml for hexane, DCM, ethyl acetate, methanol and quarcetine respectively.
10aAntioxidant activity10aAquilaria malaccensis10aIC50 value1 aA.W.N, Huda1 aM.A.S, Munira1 aS.D, Fitrya1 aM, Salmah uhttps://www.phcogres.com/article/2009/1/5/nil-4