Pharmacognosy Research
Journal Impact
(As per Journal Citation Reports 2026)
Category: Pharmacology, Toxicology and Pharmaceutics > Drug Discovery and Pharmaceutical Science
Sources: Journal Citation Reports from Clarivate, 2026 release.
Pharmacognosy Research
Volume 19, Issue 1 • 2027
Shenmai Injection Attenuates Pressure Overload-Induced Cardiac Hypertrophy by Modulating HRAS
Background/Objectives: Pressure overload-induced cardiac hypertrophy is a critical pathological precursor in the development of heart failure. Shenmai Injection (SMI) is widely used to treat cardiovascular diseases. However, its anti-hypertrophic effects and underlying molecular mechanisms remain insufficiently elucida


Comparative Pharmaceutical and Analytical Evaluation of Shoolaharana Yoga: Bhavita Formulation Versus Hydroalcoholic Extract
Background: Shoolaharana Yoga, described in Rasendra Sara Saṃgraha, is a classical Herbo-mineral formulation indicated for various types of pain. Ayurvedic pharmaceutical processes such as Shodhana (Purification) and Bhavana (Trituration) are traditionally employed to enhance safety, bioavailability, and therapeutic po

Targeted Neurotherapeutics: A Review of Bacopa monnieri Delivery Strategies for Neurodegeneration
Neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and Autism lead to Central Nervous System (CNS) degeneration, impairing both cognitive and motor functions. With the rising prevalence of these illnesses-closely linked to age and lifestyle factors-effective therapeutic strategies that can cr

Comparative Structural and Biophysical Profiling of Dengue Virus NS5 Methyltransferase Identifies DENV-4 as a Prioritized Antiviral Target
Background: The NS5 Methyltransferase (MTase) domain is essential for the capping and replication of dengue virus RNA and for the virus's evasion of the host immune response, making it a promising antiviral target. Purpose: To assess the structural and biophysical characteristics of the NS5 MTase across the four Dengu

Anticancer Effects of Schinus molle-Synthesized Iron Nanoparticles in Human Hela Cervical Cancer Cells
Objectives: Green development of iron nanoparticles by plant derived extracts has collected important scientific attention due to their eco-friendly fabrication, cost-effectiveness, and enhanced biological activities. Materials and Methods: The current research was assumed to evaluate the anticancer efficacy of Iron N

Daidzein Attenuates Allergic Asthma via NF-κB1 Downregulation and Cytokine Modulation: A Comprehensive Preclinical Evaluation
Background: Bronchial Asthma (BA) is a chronic inflammatory airway disorder strongly associated with immune system dysregulation. Daidzein, a natural isoflavone found in soy, exhibits well-documented anti-inflammatory and immunomodulatory activities, including inhibition of dendritic cell maturation and regulation of e

Comparative Analysis of Multi-Solvent Tinospora cordifolia Fresh and Dry Leaf Extract Using Advanced Analytical Approaches
Background: Tinospora cordifolia is used worldwide for its medicinal properties, but its bioactive phytoconstituents have been less explored. Objectives: The fresh and dry leaf extracts of Tinospora cordifolia, a traditional medicinal plant, were comparatively analysed for their phytochemical content and therapeutic p

Taxonomic Characterization and Ethnobotanical Insights of Bergenia ciliata Used by Hakeems in the Kashmir Himalaya
Background: The Kashmir Himalaya is known for its rich diversity of medicinal plants that support traditional healthcare systems, where indigenous knowledge plays a vital role in disease management. Among these, Bergenia ciliata is widely recognized for its therapeutic potential; however, comprehensive studies integrat

Identification of Potential Plant-Based Bioactive Compounds as α-Synuclein Targets via Molecular Docking and Molecular Dynamics Simulations
Introduction: Parkinson’s Disease (PD) is a distressing neurodegenerative ailment that involves the demise of neurons present in dopaminergic system and continuous progression of α-synuclein into amyloid fibrils. Combating α-synuclein aggregation represents an intriguing approach to develop disease-modifying therapy.

Phytochemical Profiling of Unripe Fruits of Ficus carica and Phyllanthus emblica Grown in West Bengal and Evaluation of their in vitro Antidiabetic and Anti-Inflammatory Activity
Background: Unripe fruits are promising sources of nutrition in the daily diet, which have gained attention for their rich phytochemical profile and associated health benefits. Objectives: The present study aimed to profile the phytochemical constituents of unripe fruits of Ficus carica and Phyllanthus emblica grown i

GC-MS Phytochemical Profiling of Kaidarya Siddha Narikela Taila: Mechanistic Insights into Khalitya (Non-Specific Hairfall) Management
Background: Non-Specific Hairfall (NSHF), classified as Khalitya in Ayurveda (NAMC FA-3, ICD-11 TM2), has a significant global burden. Kaidarya siddha Narikela Taila (KNT) is a formulation prepared with Narikela Taila (Cocos nucifera) and Kaidarya kashaya (decoction of Murraya koenigii), widely utilised in the manageme

High Performance Thin Layer Chromatography (HPTLC) Methods for Simultaneous Estimation and Quantification of Vasicine, Gallic acid, Piperine and Pterostilbene from Two Ayurvedic Formulations and Herbal Extracts
Background: High Performance Thin Layer Chromatography (HPTLC) is an advanced analytical technique used for the identification and quantification of marker compounds in Ayurvedic formulations. Aims and Objectives: The purpose of this study is to create and validate an HPTLC method for the simultaneous estimation and q

Comparative In vitro Evaluation of Chemical and Herbal Antimicrobial Agents for Surface Decontamination: A Pharmaceutical Perspective
Background: Maintenance of asepsis is essential for successful endodontic therapy. Gutta-percha cones are susceptible to microbial contamination during handling and storage, and their thermoplastic nature precludes heat sterilization, making rapid chemical disinfection necessary. Purpose: This study evaluated the comp
