Pharmacognosy Research
Journal Impact
(As per Journal Citation Reports 2026)
Category: Pharmacology, Toxicology and Pharmaceutics > Drug Discovery and Pharmaceutical Science
Sources: Journal Citation Reports from Clarivate, 2026 release.
Pharmacognosy Research
Volume 19, Issue 1 • 2027
Comparative Structural and Biophysical Profiling of Dengue Virus NS5 Methyltransferase Identifies DENV-4 as a Prioritized Antiviral Target
Background: The NS5 Methyltransferase (MTase) domain is essential for the capping and replication of dengue virus RNA and for the virus's evasion of the host immune response, making it a promising antiviral target. Purpose: To assess the structural and biophysical characteristics of the NS5 MTase across the four Dengu


Identification of Potential Plant-Based Bioactive Compounds as α-Synuclein Targets via Molecular Docking and Molecular Dynamics Simulations
Introduction: Parkinson’s Disease (PD) is a distressing neurodegenerative ailment that involves the demise of neurons present in dopaminergic system and continuous progression of α-synuclein into amyloid fibrils. Combating α-synuclein aggregation represents an intriguing approach to develop disease-modifying therapy.

Modulation of KEAP1/NRF2-Regulated Anticancer Chemopreventive Signalling Pathways by Anacardic Acid in MCF7-ARE Human Breast Cancer Cells
Background: Breast cancer is the most diagnosed cancer worldwide, with an escalating burden over the past decades. Anacardic Acid (AA), a phenolic lipid extracted from cashew nutshell, displays diverse therapeutic properties including anti-tumor effects. However, the molecular mechanisms underlying the anticancer effec

Comparative Analysis of Multi-Solvent Tinospora cordifolia Fresh and Dry Leaf Extract Using Advanced Analytical Approaches
Background: Tinospora cordifolia is used worldwide for its medicinal properties, but its bioactive phytoconstituents have been less explored. Objectives: The fresh and dry leaf extracts of Tinospora cordifolia, a traditional medicinal plant, were comparatively analysed for their phytochemical content and therapeutic p

Development and Quality Assessment of Poshakriti: A Gluten-Free, Multipurpose, Multigrain, Nutritional Flour
Background: Growing awareness of the health-nutrition interface and demand for convenient yet wholesome foods is rising. Traditional Indian diets, influenced by Ayurvedic principles, emphasize balanced combinations of cereals, pulses, and spices. Objectives: Building on this knowledge, a novel gluten-free, millet-rich

Characterization and Chromatographic Evaluation of Shatapushpadi Lepa
Background: Shatapushpadi Lepa is a traditional external application specified in Ayurveda. The composition that is advised for Vata-dominant inflammatory joint diseases. To determine quality, and therapeutic effectiveness, such a conventional formulation must be scientifically validated. Purpose: The present study is

Pharmacognostical Standardization of Leaf and Stem Bark of Elaeodendron glaucum (Rottb.) Pers.- An Important Ethno-Medicinal Plant
Background: Elaeodendron glaucum (Rottb.) Pers. is an essential ethnomedicinal plant belonging to Celastraceae used in the treatment of various ailments like antidotes for snake bites, dog bites, wounds and cracks, dysuria, swellings, burning sensations, hyperacidity, dysentery, headaches, fever, etc. Aim: The Present

Daidzein Attenuates Allergic Asthma via NF-κB1 Downregulation and Cytokine Modulation: A Comprehensive Preclinical Evaluation
Background: Bronchial Asthma (BA) is a chronic inflammatory airway disorder strongly associated with immune system dysregulation. Daidzein, a natural isoflavone found in soy, exhibits well-documented anti-inflammatory and immunomodulatory activities, including inhibition of dendritic cell maturation and regulation of e

Natural Products in Dental Care (2010-2026): A Narrative Review of Efficacy, Clinical Utility, and Research Gaps
Plant byproducts have been used as supplements owing to their antimicrobial, antioxidant, and anti-inflammatory properties. They also help treat and prevent many dental problems. However, the use of herbal treatments presents challenges for researchers. This narrative review highlights the evidence of the most clinical

Green-Synthesized Tribulus terrestris-Mediated CuO Nanoparticle-Loaded CS/PVA Hydrogels: A Multifunctional Platform for Cancer Therapy and Antidiabetic Applications
Objectives: In this work, we report on the preparation of CuO nanoparticles using extract from Tribulus terrestris as a natural reducing and stabilizing agent, followed by the loading of the nanoparticles into the Chitosan/Poly (vinyl alcohol) (CS/PVA) hydrogel in order to design a multifunctional system for treating c

A Study on the Pharmacognosy Materials of Ancient Traditional Medicine Prescriptions Used to Treat Bubonic Plague
Background: Ancient Mongolian doctors and scholar-monks identified diseases that were prevalent among Mongolians but were not described in Indian Ayurveda or Tibetan medicine. Based on the theory of wind, bile, and phlegm, they revised the classification of diseases to incorporate these conditions. A notable example is

Shenmai Injection Attenuates Pressure Overload-Induced Cardiac Hypertrophy by Modulating HRAS
Background/Objectives: Pressure overload-induced cardiac hypertrophy is a critical pathological precursor in the development of heart failure. Shenmai Injection (SMI) is widely used to treat cardiovascular diseases. However, its anti-hypertrophic effects and underlying molecular mechanisms remain insufficiently elucida

Targeted Neurotherapeutics: A Review of Bacopa monnieri Delivery Strategies for Neurodegeneration
Neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and Autism lead to Central Nervous System (CNS) degeneration, impairing both cognitive and motor functions. With the rising prevalence of these illnesses-closely linked to age and lifestyle factors-effective therapeutic strategies that can cr
