Pharmacognosy Research
Journal Impact
(As per Journal Citation Reports 2026)
Category: Pharmacology, Toxicology and Pharmaceutics > Drug Discovery and Pharmaceutical Science
Sources: Journal Citation Reports from Clarivate, 2026 release.
Pharmacognosy Research
Volume 19, Issue 1 • 2027
Modulation of KEAP1/NRF2-Regulated Anticancer Chemopreventive Signalling Pathways by Anacardic Acid in MCF7-ARE Human Breast Cancer Cells
Background: Breast cancer is the most diagnosed cancer worldwide, with an escalating burden over the past decades. Anacardic Acid (AA), a phenolic lipid extracted from cashew nutshell, displays diverse therapeutic properties including anti-tumor effects. However, the molecular mechanisms underlying the anticancer effec
Pharmacognostical Standardization of Leaf and Stem Bark of Elaeodendron glaucum (Rottb.) Pers.- An Important Ethno-Medicinal Plant
Background: Elaeodendron glaucum (Rottb.) Pers. is an essential ethnomedicinal plant belonging to Celastraceae used in the treatment of various ailments like antidotes for snake bites, dog bites, wounds and cracks, dysuria, swellings, burning sensations, hyperacidity, dysentery, headaches, fever, etc. Aim: The Present
Isolation and Characterization of Saponins from Asparagus racemosus: A HPTLC and LC-MS Study
Background: Shatavari or Asparagus racemosus Wild. Family Liliaceae is an important therapeutic herb in the health care system. It contains a sapogenin content which is a precursor of many pharmacologically active steroids. This plant is used to induce menstruation and as a cosmetic tonic. Objectives: The objective of
Anticancer Potential of Tephrosia maxima: Inhibition of Cell Viability and Colony Forming Ability in Oral Squamous Cell Carcinoma Cell Lines
Introduction: Oral Squamous Cell Carcinoma (OSCC) continues to be a significant global health challenge, especially in developing areas, where lifestyle associated risk factors increase its prevalence. Even with improvements in surgery, radiotherapy, and chemoradiation, toxicities related to treatment and resistance st
Comparative Structural and Biophysical Profiling of Dengue Virus NS5 Methyltransferase Identifies DENV-4 as a Prioritized Antiviral Target
Background: The NS5 Methyltransferase (MTase) domain is essential for the capping and replication of dengue virus RNA and for the virus's evasion of the host immune response, making it a promising antiviral target. Purpose: To assess the structural and biophysical characteristics of the NS5 MTase across the four Dengu
Anticancer Effects of Schinus molle-Synthesized Iron Nanoparticles in Human Hela Cervical Cancer Cells
Objectives: Green development of iron nanoparticles by plant derived extracts has collected important scientific attention due to their eco-friendly fabrication, cost-effectiveness, and enhanced biological activities. Materials and Methods: The current research was assumed to evaluate the anticancer efficacy of Iron N
Daidzein Attenuates Allergic Asthma via NF-κB1 Downregulation and Cytokine Modulation: A Comprehensive Preclinical Evaluation
Background: Bronchial Asthma (BA) is a chronic inflammatory airway disorder strongly associated with immune system dysregulation. Daidzein, a natural isoflavone found in soy, exhibits well-documented anti-inflammatory and immunomodulatory activities, including inhibition of dendritic cell maturation and regulation of e
Camellia sinensis Extract Mediated Synthesis of Fe3O4 Magnetic Nanoparticles for pH-Responsive Targeted Breast Cancer Therapy
Objectives: One challenge in treating breast cancer is that there are not enough drug delivery systems that can both target tumors specifically and have their own pharmacological effects. Materials and Methods: This study prepared Fe3O4 Magnetic Nanoparticles (Cs-MNPs) from a one-pot aqueous reaction using Camellia si
Comparative GC-MS Profiling of n-Hexane Extracts from the Heartwood and Small Branches of Pterocarpus santalinus Linn.f.
Background: Pterocarpus santalinus Linn.f. (Red Sandalwood) is an important medicinal plant known for its diverse bio active compounds. Evaluation of its phytoconstituents is essential for ensuring its therapeutic potential and quality. Chromatographic and mass spectrometric techniques are effective tools for profiling
Phytochemical and Pharmacological Potential of Pithecellobium dulce: A Review
Pithecellobium dulce (Roxb.) Benth is a medicinal plant that is commonly used in traditional medicine and its phytochemical profile has shown to contain numerous bioactive compounds which are characterized by the presence of high concentration of flavonoids (42-57 mg QE/g), phenolics (30-75 mg GAE/g), tannins, alkaloid
Natural Products in Dental Care (2010-2026): A Narrative Review of Efficacy, Clinical Utility, and Research Gaps
Plant byproducts have been used as supplements owing to their antimicrobial, antioxidant, and anti-inflammatory properties. They also help treat and prevent many dental problems. However, the use of herbal treatments presents challenges for researchers. This narrative review highlights the evidence of the most clinical
Green-Synthesized Tribulus terrestris-Mediated CuO Nanoparticle-Loaded CS/PVA Hydrogels: A Multifunctional Platform for Cancer Therapy and Antidiabetic Applications
Objectives: In this work, we report on the preparation of CuO nanoparticles using extract from Tribulus terrestris as a natural reducing and stabilizing agent, followed by the loading of the nanoparticles into the Chitosan/Poly (vinyl alcohol) (CS/PVA) hydrogel in order to design a multifunctional system for treating c
Metabolomics Insight into PN01 and SA02: Anticancer Efficacy and Antidiabetic Enzyme Inhibition
Background: Cancer is a major global health problem, with nearly 10 million deaths recorded in 2020. Approximately 30% of cancers in low- and lower-middle-income nations stem from infectious agents like Human Papillomavirus (HPV). Cervical Cancer (CC03) and HPV is now current issue all over the world especially Pakista