Pharmacognosy Research
Journal Impact
(As per Journal Citation Reports 2026)
Category: Pharmacology, Toxicology and Pharmaceutics > Drug Discovery and Pharmaceutical Science
Sources: Journal Citation Reports from Clarivate, 2026 release.
Pharmacognosy Research
Volume 18, Issue 4 • 2026
Molecular Docking Analysis of Onion Bioactives and Amino Acids to PDE-5, iNOS, AR, and D2R in Diabetic Erectile Dysfunction: A Multi-Targeted Approach
Background: Diabetic erectile dysfunction is a complex disorder involving impaired nitric oxide bioavailability, endothelial dysfunction, altered androgen signaling, and neurohormonal dysregulation. Conventional phosphodiesterase-5 inhibitors show reduced efficacy in diabetic patients and do not adequately target these


Pharmacognostic Standardization and Chromatographic Profiling of Indian Folklore Medicinal Plant Kesaraj- Wedelia chinensis
Background: Wedelia chinensis (Asteraceae) is a traditionally used medicinal herb. Despite its extensive ethnomedicinal use, comprehensive Pharmacognostic and Phytochemical standards are required for proper identification, authentication, and quality control of the crude drug. Objectives: The present study was underta

The Role of Herbal Supplements in Alleviating Menopause Symptoms
Menopause is a natural physiological change in women characterized by decreased ovarian hormone production, which causes a variety of symptoms such as hot flashes, nocturnal sweats, mood swings, sleep difficulties, and diminished bone density. Although Hormone Replacement Therapy (HRT) is commonly used to treat these s

HPTLC-Based Phytochemical Profiling and Quality Control Evaluation of Sarivadi Lauha with Relevance to Diabetic Neuropathy
Background: Sarivadi Lauha is a classical Ayurvedic herbo-mineral formulation widely used in the management of metabolic disorders. Standardisation of such formulations is essential to ensure quality, safety, and reproducibility. Objectives: To evaluate the physicochemical parameters and develop an HPTLC fingerprint p

In vitro Elucidation of Antidiabetic and Antioxidant Activities with Phytochemical Profiling of Root Extract of Paeonia emodi Wall. ex Royle Traditionally Used Plant
Background/Objectives: The present study explores the antioxidant and antidiabetic potential of Paeonia emodi Wall. ex Royle, known as Chandra which is the member of family Paeoniaceae, traditionally utilized by local inhabitants of the Chamoli district, Uttarakhand, for managing diabetes. The selection of this plant w

Regulatory Mechanisms of Cell Death Induced by Lactobacillus buchneri, Chlorella vulgaris Probiotics, and Chitosan-Conjugated Phytochemicals in Pancreatic Cancer Cells
Background and Aim: This study explores the therapeutic potential of natural compounds on pancreatic cancer cell lines (Panc-1). The main objective is to assess the effects of Lactobacillus buchneri supernatant, chitosan nanoparticles conjugated with Genistein (GCNPs), chitosan nanoparticles containing Epigallocatechin

Multi-Target Neuroprotective Activity of the Traditional Thai Polyherbal Formula Sangvichai against Amyloid-β42-Induced Cellular Stress: An in vitro Study
Background: Sangvichai is a traditional Thai polyherbal formula composed of 40 botanical ingredients and has been used for neurological complaints and age-related cognitive decline. However, scientific evidence supporting its neuroprotective effects and underlying mechanisms remains limited. Objectives: This study aim

Pongamia pinnata Stem Bark Extract Induced Changes in Testicular Function in Male Wistar Rats
Background: Pongamia pinnata (Linn.) Pierre (Fabaceae), commonly known as Karanja, is widely used in traditional medicine for the treatment of various disorders and is known to possess diverse pharmacological activities. Objectives: The present study was designed to evaluate the effects of a 50% ethanolic stem bark ex

Theaflavin Attenuates Arecoline-induced M1 Polarization and Promotes Homeostasis in Human Periodontal Ligament Fibroblasts
Background: Periodontal Ligament cells (PDL) functions as a bridge between the tooth and bone and playing a vital role in oral health. Periodontitis is an inflammatory condition that leads to dysfunction of Periodontal Ligament (PDL) cells, resulting in pyroptosis. Arecoline is a well-known alkaloid that produce excess

AI-Based Theranostic System Using Bacopa monnieri-Loaded Magnetic Nanoparticles for Alzheimer’s Disease
Background: Alzheimer’s Disease (AD) is one of the progressive neurodegenerative disorders which have a complex pathology and very limited therapeutic options. Objectives: This study presents a dual-purpose theranostic approach integrating Artificial Intelligence (AI)-based diagnosis with a nasal drug delivery system

Pharmaceutical Standardization of Shilasindur: A Comparative Study of Formulation Techniques and Analytical Methods
Background: Shilasindur (SS) is a mercurial Kupipakwa rasayan (sublime product) composed of purified mercury (Parada), sulphur (Gandhaka), and realgar (Manahshila). Traditionally used to treat skin and respiratory disorders, this study aims to evaluate and establish pharmaceutical and analytical standardization for SS

Gelatin-Alginate Biopolymeric Matrix Enriched with Punica granatum and Moringa oleifera: In vitro Biological Evaluation for the Management of Periodontal Disease
Background: Periodontal disease is a chronic inflammatory disorder characterized by microbial dysbiosis, oxidative stress, and exaggerated host immune response, leading to progressive periodontal tissue destruction. Natural phytoconstituents with antioxidant and anti-inflammatory properties have gained attention as pot

Stress-Induced Phytochemical Enhancement and in vitro Antidiabetic and Anti-Inflammatory Activities of Soil-Grown Urad Microgreens: A Comparative Study
Objectives: Microgreens are tender edible seedlings harvested 7-21 days after germination at a height of 2.5-7.5 cm. They are rich in bioactive compounds and possess potential health benefits. The present study aimed to quantify major phytochemicals, including phenolics and flavonoids, in urad (Vigna mungo) microgreens
