Exploring the Mechanisms and Dosages of Herbal Hepatoprotective Agents

Articles

Abstract
Pharmacognosy Research,2024,16,4,706-717.
Published:October 2024
Type:Review Article
Authors:
Author(s) affiliations:

Rajendra Prasad Menasagere Rajappa1,2, Paramakrishnan Nallupillai1,* , Kamsagara Linganna Krishna3, Manoj Madanahalli Ramesh4, Annegowda Hardur Venkatappa4

1Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Bannimantap, Mysuru, Karnataka, INDIA.

2Department of Pharmacognosy, Farooqia College of Pharmacy, Mysore, Karnataka, INDIA.

3Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Bannimantap, Mysuru, Karnataka, INDIA.

4Department of Pharmacognosy, Sri Adichunchanagiri College of Pharmacy, Faculty of Pharmacy, Adichunchanagiri University, BG Nagara, Mandya, Karnataka, INDIA.

Abstract:

Herbal hepatoprotective drugs are important for managing liver health because they provide complementary or alternative treatments for the various disorders of the liver. This review provides a thorough analysis of the numerous herbal hepatoprotective drugs' studied during the recent years, including their modes of action, suggested dosages, market trends, status of clinical trials and patents. The hepatoprotective properties of these herbal medicinal products are partly attributed to their mechanisms of actions such as antioxidant, anti-inflammatory, enzyme-modulating actions, and regeneration of hepatocytes. The recommended dosages differ based on the particular plant and ailment, highlighting the necessity for individualized treatment plans and more research to achieve the best possible therapeutic results. Patented compositions and polyherbal formulations provide novel treatments with synergistic effects that improve medicinal efficacy. The increased demand for natural treatments and their potential applications in pharmaceutical and nutraceutical fields has resulted in a considerable and expanding market for herbal hepatoprotective agents. Notwithstanding their possible advantages, more investigation is required to clarify mechanisms of action, assess long-term safety and efficacy, and provide uniform standards for clinical application. In general, herbal hepatoprotective drugs are promising approaches to manage liver health; nonetheless, their use necessitates regulatory oversight, quality control procedures, and evidence-based practice.

PDF
Current View
Click here to download the PDF file.
Images

Hepatoprotective herbal medicinal plants, their marketed products and mechanisms of liver damage and how these herbs offer protection through antioxidant and anti-inflammatory properties.

Keywords

Cite This Article