Chemical Characterization of Two Botanicals from Genus Alternanthera - A. brasiliana (L.) Kuntze and A. paronychioides A. St.-Hil

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Abstract
Pharmacognosy Research,2023,16,1,42-50.
Published:December 2023
Type:Original Article
Authors:
Author(s) affiliations:

Achintya Kumar Mandal1, Rajesh Allu1, Rajesh Chandran1, Divya Kallingil Gopi2, Sunil Kumar Koppala Narayana2, Radha Prakasam3, Shakila Ramachandran1,*

1Department of Chemistry, Siddha Central Research Institute (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA.

2Department of Pharmacognosy, Siddha Central Research Institute (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA.

3Siddha Medicinal Plants Garden (Central Council for Research in Siddha, Ministry of Ayush, Government of India), Mettur Dam, Salem, Tamil Nadu, INDIA.

Abstract:

Background: Traditional medicine has become part and parcel of the present era for the maintaining and preventing of ailments. Alternanthera brasiliana and Alternanthera paronychioides (Amaranthaceae) are widely used in traditional medicine. Ab is widely familiar as penicillin in Brazil. Ap is known to treat gout, hyperuricemia, rheumatic arthritis, nephritis etc. as folk medicine. The present study aims to compare standardization profiles for A. brasiliana and A. paronychioides. Materials and Methods: Sample Ab and Ap were collected and authenticated. Authenticated samples were subjected to powder microscopy, physico-chemical, phytochemical, HPTLC and HPLC fingerprint and PXRD analysis. Results: Powder microscopic investigations revealed the characteristic features for identification. Physico-chemical investigation revealed the slightly acidic nature of both plants. The phytochemical test showed the existence of phenol, terpenoids and steroids as major secondary metabolites in both species. Photo documentation, fingerprints and spectral comparison by HPTLC and fingerprints by HPLC validate the existence of similar compounds in both Ab and Ap. PXRD analysis revealed the variance of elements present in both species. Conclusion: Comparative physico-chemical, phytochemical and HPLC, HPTLC, and P-XRD instrumental analysis of A. brasiliana and A. paronychioides provides distinct features for identification.

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Aerial parts of A. brasiliana and A. paronychioides

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