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Cycloolivil, a lignan from the roots of Stereospermum suaveolens

1, 2★, 2, 2, 2, 2★ Corresponding author

  1. 1Pharmacognosy, Government College of Pharmacy
  2. 2Departments of Phytochemistry, Natural Remedies Pvt. Ltd. Bangalore, Karnataka, India

CORRESPONDENCE

Janani Jacob

Departments of Phytochemistry, Natural Remedies Pvt. Ltd. Bangalore, Karnataka, India

janani@naturalremedy.com

Volume 7, Issue 1 · pp. 45-48 · 2014 · DOI: 10.4103/0974-8490.147198

ABSTRACT

Stereospermum suaveolens DC. (Syn. S. chelonoides) belonging to family Bignoniaceae is an important medicinal plant in India. Traditionally, it is mainly used as analgesic, liver stimulant, astringent, wound healing and antidyspeptic. Roots of this plant are one of the ingredients of Dashamularishta. The plant has been studied for many pharmacological actions, only few were concerned with isolation of active compounds. The present work deals with the isolation and identification of phytochemical constituents present in the roots of Stereospermum suaveolens. The compounds were isolated from the ethyl acetate-soluble fraction from the methanol extract of S. suaveolens by using open silica gel column chromatography and HPLC was carried out for all the fractions to target the major peaks in fractions. The isolated compounds structures were elucidated by analysis of spectroscopic data (UV, IR, 1D-NMR, and MS) and characterized as Cycloolivil (1) reported for the first time from this plant species, Lapachol (2) and b-sitosterol (3), respectively.

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    Sab, B. A. W., Jacob, J., Manjunath, G. G., Singh, V. K., Mundkinajeedu, D., & Shankarappa, S. (2014). Cycloolivil, a lignan from the roots of Stereospermum suaveolens. Pharmacognosy Research, 7(1), 45-48. https://doi.org/10.4103/0974-8490.147198

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    © 2014 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0