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The optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method

1, 1, 2, 1★★ Corresponding author

  1. 1Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd
  2. 2Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

CORRESPONDENCE

Alireza Nematollahi

Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd

alireza_nemat@yahoo.com

Volume 7, Issue 1 · pp. 57-65 · 2014 · DOI: 10.4103/0974-8490.147209

ABSTRACT

The aim of this study was to examine and evaluate crucial variables in essential oils extraction process from Lavandula hybrida through static-dynamic and semi-continuous techniques using response surface method. Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique. Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5°C, 120 min (static: 8×15), 24 min (dynamic: 8×3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2°C, 14 min (static), 121.1 min (dynamic). The results indicated that a substantial reduction (81.56%) solvent usage (kg CO2/g oil) is observed in the SDS method versus the conventional SC method.

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    Kamali, H., Aminimoghadamfarouj, N., Golmakani, E., & Nematollahi, A. (2014). The optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method. Pharmacognosy Research, 7(1), 57-65. https://doi.org/10.4103/0974-8490.147209

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    © 2014 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0