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GC-MS analysis of bioactive compounds in the methanol extract of Clerodendrum viscosum leaves

1★, 1, 2, 2, 3, 1★ Corresponding author

  1. 1Department of Pharmacognosy, School of Pharmaceutical Sciences
  2. 2Departments of Pharmacology
  3. 3Departments of Medicinal Chemistry, Institute of Medical Science, Siksha ‘O’ Anusandhan University, Bhubaneswar, Odisha, India

CORRESPONDENCE

Goutam Ghosh

Department of Pharmacognosy, School of Pharmaceutical Sciences

goutamghoshsps@gmail.com

Volume 7, Issue 1 · pp. 110-113 · 2014 · DOI: 10.4103/0974-8490.147223

ABSTRACT

Clerodendrum viscosum is commonly found in India and Bangladesh. Previously, various parts of this plant were reported for treatment of different types of diseases and there was no report on GC-Ms analysis. To analyze and characterize the phytochemical compounds of methanol extract of Clerodendrum viscosum using GC-MS. The preliminary phytochemical screening of methanol extract was carried out according to standard procedures described in WHO guidelines. Various bioactive compounds of the extract were determined by GC-MS technique. The presence of steroids, triterpenoids, alkaloids, saponins, flavonoids, tannins and carbohydrate was found on phytochemical screening of methanol extract of the leaves. The GC-MS analysis showed 16 peaks of different phytoconstituents namely acetamide,N,N-carbonylbis-, 4-Pyranone,2,3-dihydro-, alpha-D-Galactofuranoside, methyl 2,3,5,6-tetra-O-methyl-, Glycerin, Xylitol, N,N-Dimethylglycine, 4H-Pyran-4-one,2,3-dihydro-3, 5-dihydroxy-6- methyl-, Benzofuran,2,3-dihydro-, 5-Hydroxymethylfurfural, 2(1H)Pyrimidinone,1-methyl-, 2,4-Dihydroxy-5,6-dimethylpyrimidine, 3-Deoxy-d-mannoic lactone, 1,3-Methylene-d- arabitol, Orcinol, n-Hexadecanoic acid and Phenol,4,4'-(1-methyl ethylidene) bis etc. The bioactive compounds present in the methanol extract of Clerodendrum viscosum suggest the application of this extract for the treatment of various diseases by the aborigine tribes.

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    Ghosh, G., Panda, P., Rath, M., Pal, A., Sharma, T., & Das, D. (2014). GC-MS analysis of bioactive compounds in the methanol extract of Clerodendrum viscosum leaves. Pharmacognosy Research, 7(1), 110-113. https://doi.org/10.4103/0974-8490.147223

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    © 2014 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0