Cytotoxic essential oil from Annona sengalensis Pers. leaves
1★, 2, 3, 2★ Corresponding author
- 1Department of Health Information Technology of Jeddah Community College, King Abdul-Aziz University, Al- Rehab 80283 Jeddah, Kingdom of Saudi Arabia
- 2Department Pharmacognosy, National Research Centre Dokki 12622 Giza, Egypt
- 3Department Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
CORRESPONDENCE
A. L. Ahmed
Department of Health Information Technology of Jeddah Community College, King Abdul-Aziz University, Al- Rehab, 80283 Jeddah, Kingdom of Saudi Arabia
Received: 30-01-2010; Accepted: 07-09-2010.
Volume 2, Issue 4 · pp. 211-214 · 2010 · DOI: 10.4103/0974-8490.69105
ABSTRACT
The cytotoxicity against brine shrimp of the essential oil obtained from the leaves of Annona senegalensis Pers. (Annonaceae) was studied. The confirmation of this toxicity has been done by using selected tumor cell lines (A549, HT29, MCF 7, RPMI, and U251). The results showed that the total oil and its fractions have showed mild to moderate cytotoxicity in brine shrimp lethality bioassay with LC50 = 27.3 μg/ml, and against some human tumor cell lines. The total oil and its fractions were analyzed by gas chromatography/mass spectroscopy (GC/MS). Seventy three compounds were identified.
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Ahmed, A. L., Bassem, S. E. M., Mohamed, Y. H., & Gamila, M. W. (2010). Cytotoxic essential oil from Annona sengalensis Pers. leaves. Pharmacognosy Research, 2(4), 211-214. https://doi.org/10.4103/0974-8490.69105
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