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PR · Lens · Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia

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Article · Volume 7, Issue 1 · pp. 14-17

Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia

Essam Abdel-Sattar1, Dina Abou-Hussein1, Frank Petereit2

  1. 1Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt
  2. 2University of Münster, Institute of Pharmaceutical Biology and Phytochemistry, Hittorfstraße 56, D-48149 Münster, Germany

Abstract

Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), D-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity.

Keywords: Cervical adenocarcinoma; euphol; Euphorbia ammak

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