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PR · Lens · Triterpenes from Euphorbia rigida

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Article · Volume 2, Issue 3 · pp. 159-162

Triterpenes from Euphorbia rigida

Noureddine Gherraf1, Amar Zellagui1, Naglaa S. Mohamed2, Taha A. Hussien3, Tarik A. Mohamed4, Mohamed-Elamir F. Hegazy5, Salah Rhouati1, Mahmoud F. M. Moustafa6, Magdi A. El-Sayed7, Abou El-Hamd H. Mohamed2

  1. 1Laboratory of Natural Products and Organic Synthesis, Department of Chemistry, Faculty of Science, University Mentouri - Constantine, Algeria
  2. 2Department of Chemistry, Aswan-Faculty of Science, South Valley University, Aswan, Egypt
  3. 3Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmacy, Applied Sciences University, Amman, Jordan - 119 31
  4. 4Department of Pharmacognosy, Faculty of Pharmacy, El-Minia University, El-Minia - 615 19
  5. 5Chemistry of Medicinal Plant Department, National Research Centre, Dokki, Giza - 126 22, Egypt
  6. 6Department of Biological Sciences, College of Science, King Khalid University, 61413, Saudi Arabia
  7. 7Botany, Aswan-Faculty of Science, South Valley University, Aswan, Egypt

Abstract

Phytochemical studies of the aerial parts of Euphorbia rigida afforded three triterpenes: betulin (1), cycloart-23Z-ene-3, 25-diol (2) and cycloartan-3, 24, 25-triol (3), firstly isolated from this plant. The structures and relative stereochemistry were determined on the basis of extensive spectroscopic analyses, including 1D and 2D NMR experiments (1H NMR, 13C NMR, COSY, NOESY, HMQC and HMBC).

Keywords: Euphorbia rigida; Euphorbiaceae; cycloartan triterpene

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