Phytochemical and Pharmacological Screening of Begonia grandis Dryand
1, 1, 2, 2, 2
- 1Research and Development Wing, Divis Laboratories Ltd, Visakhapatnam, Andhra Pradesh, INDIA.
- 2GITAM Institute of Pharmacy, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, INDIA.
CORRESPONDENCE
Ganapaty Seru
GITAM Institute of Pharmacy, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, INDIA.
Received: 08-07-2020; Accepted: 15-09-2020.
Volume 12, Issue 4 · pp. 375-379 · 2021 · DOI: 10.4103/pr.pr_67_20
ABSTRACT
Begonia grandis Dryand (Family: Begoniaceae) was screened for its phytoconstituents and evaluated for its ethnomedicinal potential as an antioxidant and hepatoprotective agent. The preliminary phytochemical studies of the B. grandis revealed the presence of alkaloids, flavonoids, glycosides, triterpenoids, and steroids. Antioxidant effect of the methanolic extract was assessed by DPPH, superoxide, hydroxyl radical scavenging activity, and hepatoprotective effect by CCl4-induced hepatotoxicity. The extract showed significant antioxidant and hepatoprotective effects at a dose of 400 mg/kg similar to that observed in ascorbic acid and silymarin.
KEYWORDS
REFERENCES
As publishedShowing references and in-text citations exactly as published.
Cite this article
SELECT FORMAT
Pendy, S., Nallamothu, K., Seru, G., Katta, S., & Mondal, S. (2021). Phytochemical and Pharmacological Screening of Begonia grandis Dryand. Pharmacognosy Research, 12(4), 375-379. https://doi.org/10.4103/pr.pr_67_20
Copyright and licence
© 2021 Author(s)
This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0