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  Indian J Med Microbiol
 

Figure 5: Effect of Antrocaryon micraster on mucosal mast cell stability. Rats received daily administration of either normal saline, sulphasalazine 500 mg/kg, or Antrocaryon micraster extract (30, 100, and 300 mg/kg) for 3 days. Colitis was induced as described in the method. Colons were removed after 24 h and stained with toluidine blue. Photographs were obtained at ×400. (a) Representative photomicrographs of noncolitic control (1), acetic acid control (2), sulphasalazine 500 mg/kg (3), Antrocaryon micraster extract 30 mg/kg (4), Antrocaryon micraster extract 100 mg/kg (5), and Antrocaryon micraster extract 300 mg/kg (6). Percentage degranulated mast cells were calculated (b). Data are presented as mean ± standard error of mean (n = 5). **P < 0.01 and ***P < 0.001 compared to the acetic acid control group (AA); ####P < 0.001 compared to the naive group (One-way analysis of variance followed by Dunnett's post hoc test). i: Intact mast cell, ii: Degranulated mast cell. Scale bar represents 200 μm of tissue

Figure 5: Effect of <i>Antrocaryon micraster</i> on mucosal mast cell stability. Rats received daily administration of either normal saline, sulphasalazine 500 mg/kg, or <i>Antrocaryon micraster</i> extract (30, 100, and 300 mg/kg) for 3 days. Colitis was induced as described in the method. Colons were removed after 24 h and stained with toluidine blue. Photographs were obtained at ×400. (a) Representative photomicrographs of noncolitic control (1), acetic acid control (2), sulphasalazine 500 mg/kg (3), <i>Antrocaryon micraster</i> extract 30 mg/kg (4), <i>Antrocaryon micraster</i> extract 100 mg/kg (5), and <i>Antrocaryon micraster</i> extract 300 mg/kg (6). Percentage degranulated mast cells were calculated (b). Data are presented as mean ± standard error of mean (<i>n</i> = 5). **<i>P</i> < 0.01 and ***<i>P</i> < 0.001 compared to the acetic acid control group (AA); ####<i>P</i> < 0.001 compared to the naive group (One-way analysis of variance followed by Dunnett's post hoc test). i: Intact mast cell, ii: Degranulated mast cell. Scale bar represents 200 μm of tissue