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  Indian J Med Microbiol
 

Figure 3: Effect of Antrocaryon micraster extract on macroscopic damage in colons of acetic acid-induced colitic rats. Sprague Dawley rats received either normal saline, sulphasalazine 500 mg/kg, or Antrocaryon micraster extract (30, 100, and 300 mg/kg p.o) for 3 days. Colitis was induced as described in the method. Colons were removed after 24 h, opened by longitudinal incision and photographed (a). 1: Naive control, 2: Colitic control showing diffuse erosion, 3: Colitic control showing necrosis, 4: Sulphasalazine 500 mg/kg, 5-7: Antrocaryon micraster extract 30, 100, and 300 mg/kg, respectively, and quantified (b). Data are presented as mean ± standard error of mean (n = 5). *P < 0.05, **P < 0.01, ***P < 0.001 compared to the acetic acid control group; ####P < 0.001 compared to the naive group (One-way analysis of variance followed by Dunnett's post hoc test). NS not statistically different

Figure 3: Effect of <i>Antrocaryon micraster</i> extract on macroscopic damage in colons of acetic acid-induced colitic rats. Sprague Dawley rats received either normal saline, sulphasalazine 500 mg/kg, or <i>Antrocaryon micraster</i> extract (30, 100, and 300 mg/kg p.o) for 3 days. Colitis was induced as described in the method. Colons were removed after 24 h, opened by longitudinal incision and photographed (a). 1: Naive control, 2: Colitic control showing diffuse erosion, 3: Colitic control showing necrosis, 4: Sulphasalazine 500 mg/kg, 5-7: <i>Antrocaryon micraster</i> extract 30, 100, and 300 mg/kg, respectively, and quantified (b). Data are presented as mean ± standard error of mean (<i>n</i> = 5). *<i>P <</i> 0.05, **<i>P <</i> 0.01, ***<i>P <</i> 0.001 compared to the acetic acid control group<i>; ####P <</i> 0.001 compared to the naive group (One-way analysis of variance followed by Dunnett's <i>post hoc</i> test). NS not statistically different