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  Indian J Med Microbiol
 

Figure 6: Annonacin exhibits antiproliferation effects on endometrial cancer cells through inhibition of extracellular signal-regulated kinase phosphorylation and promotion of caspase-3 cleavage. (a) Western blotting analysis of extracellular signal-regulated kinase protein expression in endometrial cancer cells after treated with control media, vehicle, or annonacin at 72 h. Data shown are representative of two independent experiments. (b) Expression of procaspase-3 and cleaved caspase-3 in endometrial cancer cells 72 h postannonacin treatment. β-actin was used as endogenous control. Data shown are representative of two independent experiments

Figure 6: Annonacin exhibits antiproliferation effects on endometrial cancer cells through inhibition of extracellular signal-regulated kinase phosphorylation and promotion of caspase-3 cleavage. (a) Western blotting analysis of extracellular signal-regulated kinase protein expression in endometrial cancer cells after treated with control media, vehicle, or annonacin at 72 h. Data shown are representative of two independent experiments. (b) Expression of procaspase-3 and cleaved caspase-3 in endometrial cancer cells 72 h postannonacin treatment. β-actin was used as endogenous control. Data shown are representative of two independent experiments