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  Indian J Med Microbiol
 

Figure 4: Analysis of mRNA expression by semiquantitative reverse transcriptase-polymerase chain reaction. (a) Bars represent densitometric analysis of connexin 43 and N-cadherin mRNA expression in control and exposed animals. (b) Changes in mRNA are expressed as normalized densitometric units relative to β-actin mRNA. Values are the mean ± standard error of mean P < 0.05 indicates statistical significance. Transcriptional levels obtained by semiquantitative reverse transcription polymerase chain reaction are shown in electrophoretic images. (*) Significant difference from the control group (*1 = 0.0001, *2 = 0.0011, *3 = 0.0107, *4 = 0.021, *5 = 0.0038, *6 = 0.0047, *7 = 0.0142 and *8 = 0.0058); (#) significant difference from the T1 group (#1 = 0.002, #2 = 0.0077, #3 = 0.0075, #4 = 0.048). Co = control; T1 = 6 mg/kg/day; T2 = 10 mg/kg/day, T3 = 15 mg/kg/day

Figure 4: Analysis of mRNA expression by semiquantitative reverse transcriptase-polymerase chain reaction. (a) Bars represent densitometric analysis of connexin 43 and N-cadherin mRNA expression in control and exposed animals. (b) Changes in mRNA are expressed as normalized densitometric units relative to β-actin mRNA. Values are the mean ± standard error of mean <i>P</i> < 0.05 indicates statistical significance. Transcriptional levels obtained by semiquantitative reverse transcription polymerase chain reaction are shown in electrophoretic images. (*) Significant difference from the control group (*1 = 0.0001, *2 = 0.0011, *3 = 0.0107, *4 = 0.021, *5 = 0.0038, *6 = 0.0047, *7 = 0.0142 and *8 = 0.0058); (#) significant difference from the T1 group (#1 = 0.002, #2 = 0.0077, #3 = 0.0075, #4 = 0.048). Co = control; T1 = 6 mg/kg/day; T2 = 10 mg/kg/day, T3 = 15 mg/kg/day