Close
  Indian J Med Microbiol
 

Figure 1: Effect of UP1304 on the glycosaminoglycan releasing assay. Cartilage explants were incubated for 24 h in Dulbecco's modified eagle medium with 1% heat-inactivated fetal bovine serum and 10 mM hydroxyethyl piperazineethanesulfonic acid. GAG releasing into the medium was significantly decreased by UP1304 treatment in a dose-dependent manner. UP1304 at concentration 200 μg/mL brought down the recombinant human interleukin-1alpha induced proteoglycan degradation to a normal level

Figure 1: Effect of UP1304 on the glycosaminoglycan releasing assay. Cartilage explants were incubated for 24 h in Dulbecco's modified eagle medium with 1% heat-inactivated fetal bovine serum and 10 mM hydroxyethyl piperazineethanesulfonic acid. GAG releasing into the medium was significantly decreased by UP1304 treatment in a dose-dependent manner. UP1304 at concentration 200 μg/mL brought down the recombinant human interleukin-1alpha induced proteoglycan degradation to a normal level