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  Indian J Med Microbiol
 

Figure 5: Putative mechanism of ameliorative effect of Psidium guajava (PG) on the onset of insulin resistance (IR). Circulating insulin and leptin modulates hepatic expression of glucose transporter (GLUT 2) that in turn mediates the flux of fructose into liver, where it is taken up by biochemical pathways leading to synthesis of triglycerides and fatty acids. Treatment with PG favorably re-sets the insulin, leptin and GLUT2 talk to ameliorate the metabolic paradigms of IR

Figure 5: Putative mechanism of ameliorative effect of <i>Psidium guajava</i> (PG) on the onset of insulin resistance (IR). Circulating insulin and leptin modulates hepatic expression of glucose transporter (GLUT 2) that in turn mediates the flux of fructose into liver, where it is taken up by biochemical pathways leading to synthesis of triglycerides and fatty acids. Treatment with PG favorably re-sets the insulin, leptin and GLUT2 talk to ameliorate the metabolic paradigms of IR