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  Indian J Med Microbiol
 

Figure 2: Effect of Vitex negundo on inhibition of cyclooxygenase. Results are expressed as mean ± SD (n = 6). *Statistically different (P < 0.05) from control rats. Expressed as COX-1: Cyclooxygenase-1; COX-2: Cyclooxygenase-2; Group (I) (control group, n = 6) treated with 1 mg diclofinac diethylamine BP and 7 mg methyl salicylate IP/kg; Groups (II, III, and IV) (treated group, n = 6): V. negundo leaf oil equivalent to 200 μl, 1000 μl, and 2000 μl diluted with paraffin oil; Group V (placebo control group, n = 6) treated with equivalent 1 ml/kg paraffin oil

Figure 2: Effect of Vitex negundo on inhibition of cyclooxygenase. Results are expressed as mean ± SD (n = 6). *Statistically different (P < 0.05) from control rats. Expressed as COX-1: Cyclooxygenase-1; COX-2: Cyclooxygenase-2; Group (I) (control group, n = 6) treated with 1 mg diclofinac diethylamine BP and 7 mg methyl salicylate IP/kg; Groups (II, III, and IV) (treated group, n = 6): V. negundo leaf oil equivalent to 200 μl, 1000 μl, and 2000 μl diluted with paraffin oil; Group V (placebo control group, n = 6) treated with equivalent 1 ml/kg paraffin oil