Pharmacognosy Research

ORIGINAL ARTICLE
Year
: 2015  |  Volume : 7  |  Issue : 1  |  Page : 57--65

The optimization of essential oils supercritical CO 2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method


Hossein Kamali1, Noushin Aminimoghadamfarouj1, Ebrahim Golmakani2, Alireza Nematollahi1 
1 Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd, Iran
2 Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Correspondence Address:
Dr. Alireza Nematollahi
Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd
Iran

Aim: The aim of this study was to examine and evaluate crucial variables in essential oils extraction process from Lavandula hybrida through static-dynamic and semi-continuous techniques using response surface method. Materials and Methods: Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique. Results: Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5° C , 120 min (static: 8×15), 24 min (dynamic: 8×3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2° C , 14 min (static), 121.1 min (dynamic). Conclusion: The results indicated that a substantial reduction (81.56%) solvent usage (kg CO 2 /g oil) is observed in the SDS method versus the conventional SC method.


How to cite this article:
Kamali H, Aminimoghadamfarouj N, Golmakani E, Nematollahi A. The optimization of essential oils supercritical CO 2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method.Phcog Res 2015;7:57-65


How to cite this URL:
Kamali H, Aminimoghadamfarouj N, Golmakani E, Nematollahi A. The optimization of essential oils supercritical CO 2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method. Phcog Res [serial online] 2015 [cited 2020 Nov 30 ];7:57-65
Available from: http://www.phcogres.com/article.asp?issn=0974-8490;year=2015;volume=7;issue=1;spage=57;epage=65;aulast=Kamali;type=0