02259nas a2200241 4500008004100000245020400041210006900245260001800314300001200332490000600344520136100350653001901711653005201730653002701782653001701809653002401826653001901850100003301869700001901902700002401921700002001945856005201965 2009 eng d00aIntestinal absorption, anti diarrheic activity of freeze dried aqueous extract from Rhizophora mangle L. Cytoprotective activity of polyphenolic compounds fractions on experimental gastric ulceration0 aIntestinal absorption anti diarrheic activity of freeze dried aq cJanuary 2010  a285-2930 v13 a

The effect of the freeze aqueous extract from red mangrove bark on intestinal absorption was studied in vitro e in situ models in rats. Anti diarrheic activity of this extract was evaluated using a model of ricin oil in rats. The polyphenolic fractions were separated from the aqueous extract and its cytoprotective activity were studied on gastric ulceration induced by ethanol plus hydrochloric acid in rats. The freeze - dried aqueous extract from red mangrove bark was used in both models employed to determinate the intestinal absorption. The freeze dried extract of R. mangle shown a high absorption. It was superiority at 95% in vitro study and the constant apparent of absorption’s rate was 2, 03 ± 0, 77. It was shown a high anti diarrheic effect of R. mangle in experimental model with ricin oil. The low molecular weigh polyphenolic fraction showed the highest level of gastric protection. Not additive effect was obtained by comparison between low and high molecular weigh polyphenols in this aqueous extract. The highest gastric protection was obtained by oral treatment with total of freeze aqueous extract at 500 mg/ kg body weight (b.w.). Probably the cytoprotective activity was resulted of other compounds presents in this extract joint at polyphenol substances.

10aCytoprotection10aIn vitro e in situ intestinal absorption models10aPolyphenolic fractions10aRed mangrove10aRhizophora mangle L10aRhizophoraceae1 aSánchez, Perera, Luz María1 aBetty, Mancebo1 aIvis, Regalado, Ada1 aLilliam, Pelzer uhttps://www.phcogres.com/article/2009/1/5/nil-7