02293nas a2200217 4500008004100000245020700041210006900248260001300317300001200330490000600342520150000348653001201848653001401860653001501874653002801889653002801917100002301945700002101968700001801989856006802007 2014 eng d00aExploiting the Phenomenal Anti-ulcerogenic Potential of Talinum portulacifolium Ethanolic Extract Whole Plant on Albino Rats: The Therapeutic Potential of Chinese Herb-mǎ chǐ xiàn kē (Portulacaceae)0 aExploiting the Phenomenal Antiulcerogenic Potential of Talinum p cMay,2014 a227-2330 v63 a

Background: Ulcerations have been effecting humans and causing major damage in the gastro intestinal tract. A need for development of a flawless anti-ulcer medication was always in the agenda. Thus, the need to conduct a study was provoked. Objectives: The major objective of the present study is to screen the antiulcer activity of the ethanolic extract of Talinum portulacifolium (Forsk) plant. Materials and Methods: The antiulcer activity of the ethanolic extract of T.Z portulacifolium was performed on albino rats. Gastric ulcers were induced by ethanol, pylorus ligated aspirin and histamine induced ulcer models. Omeprazole was used as a standard drug for comparison. Results: Treatment with the T. portulacifolium plant extract significantly protected the ulceration induced by the three models. The gastric volume, pH of gastric juice, total acidity, free acidity and ulcer index were the parameters estimated and did show significant results. 800 mg/kg extracts of T. portulacifolium did show high significant results as that of standard drug. Percentage protection of 800 mg/kg was 79.9% and the standard drug-treated group did show 84%. So was with total acidity (38.1 + 1.45) and free acidity (16.5 + 0.76) Conclusion: The ethanolic extract of T. portulacifolium plant was found to possess a significant antiulcer activity.

10aethanol10aHistamine10aOmeprazole10aPylorus-ligated aspirin10aTalinum portulacifolium1 aGundamaraju, Rohit1 aMaheedhar, Kotla1 aHwi, Kim, Kah uhttps://www.phcogres.com/article/2014/6/3/1041030974-8490132600