01886nas a2200253 4500008004100000245006400041210006200105260001800167300001000185490000600195520115700201653002001358653001701378653002001395653002101415100001701436700002401453700002301477700001901500700002501519700002101544700002101565856004601586 2009 eng d00aAntifouling Alkaloids from Crinum augustum (Amaryllidaceae)0 aAntifouling Alkaloids from Crinum augustum Amaryllidaceae cJanuary 2010 a43-520 v13 a
Fractionation and purification of the ethanolic extract of the bulbs of Crinum augustum Rox. (Amaryllidaceae) cultivated in Egypt yielded five alkaloids 6-methoxy-crinamine (1), crinamine (2), buphanisine (3), ungeremine (4), and hippadine (5); two fatty acid derivatives: myristic acid ethyl ester (6) and palmitic acid ethyl ester (7); four terpenoidal and steroidal compounds: ursolic acid (8), %-sitosterol-O- % glucopyranoside (9) and mixture of %- sitosterol (10) and stigmasterol (11). The structures of all compounds were determined by interpretation of their spectroscopic data; 1D (1H and 13C), 2D (HSQC, COSY, DQF, NOE and HMBC) NMR; MS and UV analyses. The compounds (1-4) and (6-8) were tested towards biofouling activity using larvae of barnacle Balance amphitrie. Significant activities of 1, 2 and 3 with EC50 1.8, 1.2 and 0.75 :g/mL respectively, were observed.
10aAmaryllidaceous10aAnti-fouling10aCrinum augustum10aNatural Products1 aRefaat, John1 aAbdel-Lateff, Ahmed1 aKamel, Mohamed, S.1 aAli, Ahmed, A.1 aRamadan, Mahmoud, A.1 aOkino, Tatsufumi1 aNogata, Yasuyuki uhttps://www.phcogres.com/article/2009/1/2