02255nas a2200217 4500008004100000245008900041210006900130260001800199300001000217490000600227520155300233653001901786653002201805653002801827653003301855100002801888700001801916700001801934700001701952856006801969 2014 eng d00aGC-MS Analysis of Bio-active Compounds in Methanolic Extract of Lactuca runcinata DC0 aGCMS Analysis of Bioactive Compounds in Methanolic Extract of La cDecember,2013 a58-610 v63 a

Background: The presence of phytochemical constitutes has been reported from species of the Compositae (Asteraceae). Hitherto no reports exist on the phytochemical components and biological activity of Lactuca runcinata DC. Objective: The present study was designed to determine the bioactive compounds in the whole plant methanol extract of Lactuca runcinata. Materials and Methods: Phytochemical screening of the entire herb of Lactuca runcinata DC revealed the presence of some bio-active components. Gas chromatography-mass spectrometry (GC-MS) analysis of the whole plant methanol extract of Lactuca runcinata was performed on a GC-MS equipment (Thermo Scientific Co.) Thermo GC-TRACE ultra ver.: 5.0, Thermo MS DSQ II. Results: The phytochemical tests showed the presence of alkaloids, cardiac glycosides, flavonoids, phenols, phlobatannin, reducing sugars, saponins, steroids, tannins, terpenoids, volatile oils, carbohydrates, and protein/amino acids in methanolic extract of L. runcinata. The GC-MS analysis has shown the presence of different phytochemical compounds in the methanolic extract of Lactuca runcinata. A total of 21 compounds were identified representing 84.49% of total methanolic extract composition. Conclusion: From the results, it is evident that Lactuca runcinata contains various phytocomponents and is recommended as a plant of phytopharmaceutical importance.

10aGC-MS Analysis10aLactuca runcinata10aPhytochemical screening10aWhole plant methanol extract1 aKanthal, Lakshmi, Kanta1 aDey, Akalanka1 aSatyavathi, K1 aBhojaraju, P uhttps://www.phcogres.com/article/2014/6/1/1041030974-8490122919