02611nas a2200253 4500008004100000245014600041210006900187260001800256300001000274490000600284520177800290653001602068653002202084653001702106653001702123653002102140100002502161700002402186700002302210700002302233700001502256700001802271856006802289 2014 eng d00aComparative Assessment on In vitro Antioxidant Activities of Ethanol Extracts of Averrhoa bilimbi , Gymnema Sylvestre and Capsicum Frutescens0 aComparative Assessment on In vitro Antioxidant Activities of Eth cDecember,2013 a36-410 v63 a

Background: Averrhoa bilimbi, Gymnema sylvestre and Capsicum frutescens are medicinal plants commonly used as traditional medicine for the treatment of various diseases. The present study was designed to investigate the antioxidant activities of Ethanolic extract of A. bilimbi, G. sylvestre and C. frutescens. Materials and Methods: The antioxidant activity of the extracts were evaluated using total phenolic and flavonoid contents, ferric reducing power and the free radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH). Results: Total phenolic and flavonoid contents were higher in G. sylvestre (53.63636 ΁ 0.454545 mg/g gallic acid equivalent) and C. frutescens (26.66667 ΁ 2.081666 mg/g quercetin equivalent) respectively. Reducing power of the crude ethanol extracts increased with the concentrations of the extracts and all the extracts showed moderate free radical scavenging activity against DPPH. The plant extract displayed moderate phenolic and flavonoid contents compared to gallic acid and quercetin equivalent respectively, whereas also exhibited significant scavenging of DPPH radical and reducing power compared with ascorbic acid as standard. Conclusion: Our study suggests that G. sylvestre has significant antioxidant activity. The antioxidant compound of this plant might be a therapeutic candidate against oxidative stress related diseases. Different sub-fraction of A. bilimbi and C. frutescens should be studied further to assess the effect. Further study is necessary for isolation and characterization of the active antioxidant agents for better treatment.

10aAntioxidant10aEthanolic extract10aFree radical10aG. sylvestre10aOxidative stress1 aRahman, Md., Mominur1 aHabib, Md., Razibul1 aHasan, Md., Anayet1 aAmin, Mohammad, Al1 aSaha, Ayan1 aMannan, Adnan uhttps://www.phcogres.com/article/2014/6/1/1041030974-8490122915