02078nas a2200253 4500008004100000245007100041210006900112260001700181300001200198490000600210520128600216653001701502653003101519653001201550653002001562653001701582653001401599100003601613700003401649700002401683700002901707700002001736856006801756 2015 eng d00aAmmi Visnaga in treatment of urolithiasis and hypertriglyceridemia0 aAmmi Visnaga in treatment of urolithiasis and hypertriglyceridem cOctober 2015 a397-4000 v73 a

Ammi visnaga is a widely distributed Ancient Egyptian medicinal plant used for treatment of several diseases including urolithiasis (kidney stones). The active chemical constituents’ khellin and visnagin obtained from the A. visnaga seeds have activity of antilithiogenic and pleiotropic. However, little is known about its activity on hypertriglyceridemia. The main aim of this review is to explore the use of A. visnaga in urolithiasis and to present a case of relevancy. We highlighted a case of a patient who has recurrent urethral stones and hypertriglyceridemia. The patient was treated with A. visnaga seeds, has recovered completely from ureteral stones and his high‑density lipoprotein (HDL)‑cholesterol low levels retained to normal after using of A. visnaga seeds for 10 days. The present case of A. visnaga seeds being local medicinal plant has shown the effect in treating urolithiasis with extended effect on raising HDL‑cholesterol. These results may provide insights for in vitro studies for isolation of these biologically active compounds for potential in raising HDL‑cholesterol. Whether or not the later effect can have clinical utility remains to be explored.

10aAmmi visnaga10aHigh‑density lipoprotein10aKhellin10aUreteral stones10aUrolithiasis10aVisnagin.1 aBhagavathula, Akshaya, Srikanth1 aAl‑Khatib, Ahed, Jumah Mahm1 aElnour, Asim, Ahmed1 aKalbani, Naama, M. S. Al1 aShehab, Abdulla uhttps://www.phcogres.com/article/2015/7/4/1041030974-8490167894