01889nas a2200241 4500008004100000245019400041210006900235260001800304300001000322490000600332520099800338653001801336653001301354653002201367653002801389653002701417653003401444100002001478700003301498700002301531700002501554856006801579 2015 eng d00aThe optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static‑dynamic steps procedure and semi‑continuous technique using response surface method0 aoptimization of essential oils supercritical CO2 extraction from cDecember 2014 a57-650 v73 a

Aim: The aim of this study was to examine and evaluate crucial variables in essential oils extraction process from Lavandula hybrida through static‑dynamic and semi‑continuous techniques using response surface method. Materials and Methods: Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static‑dynamic steps (SDS) procedure, and semi‑continuous (SC) technique. Results: Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5°C, 120 min (static: 8×15), 24 min (dynamic: 8×3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2°C, 14 min (static), 121.1 min (dynamic). Conclusion: The results indicated that a substantial reduction (81.56%) solvent usage (kg CO2/g oil) is observed in the SDS method versus the conventional SC method.

10aEssential oil10alavandin10aLavandula hybrida10aResponse surface method10aStatic‑dynamic steps10aSupercritical carbon dioxide.1 aKamali, Hossein1 aAminimoghadamfarouj, Noushin1 aGolmakani, Ebrahim1 aNematollahi, Alireza uhttps://www.phcogres.com/article/2015/7/1/1041030974-8490147209