02677nas a2200313 4500008004100000245011300041210006900154260001800223300001200241490000700253520159900260653001301859653001801872653002801890653002001918653001101938100002901949700002901978700002902007700003802036700003302074700003502107700003402142700002802176700003402204700003102238700003202269856006202301 2019 eng d00aPharmacognostic Evaluation of Carapa guianensis Aubl. Leaves: A Medicinal Plant Native from Brazilian Amazon0 aPharmacognostic Evaluation of Carapa guianensis Aubl Leaves A Me cNovember,2019 a333-3380 v113 a

Background: Carapa guianensis Aubl., known as crabwood, has been used in folk medicine as anti‑inflammatory, wound healing, and for the treatment of flu and colds. Objective: The present study aimed to establish the pharmacognostic features of C. guianensis leaves. Materials and Methods: The leaves were investigated according to the World Health Organization guideline on the pharmacognostic specification, which comprised macroscopic and microscopic assessment, phytochemical screening, and physicochemical characterization of the leaves, besides the microscopic analysis of the powder. Results: Leaves were characterized as a compound, coriaceous with elliptic shape, entire margin, acuminate apex, obtuse base, and opposite phyllotaxis. The epidermis has straight periclinal and anticlinal walls. Calcium oxalate crystals were observed in druses, anomocytic stomata just on a lower side (hypostomatic), and dorsiventral mesophyll. Phytochemical screening revealed the presence of flavonoids, saponins, triterpenes, and steroids in the crude extract. The values of the physicochemical parameters such as total ash, acid‑insoluble ash, and loss on drying are 7.16%, 1.03% and 7.93%, respectively; the ethanol and water‑soluble extractive values are 19.47% and 15.97%, respectively. Conclusion: The information obtained with botanical, physicochemical, and phytochemical studies could be used to identify C. guianensis and to certify the authenticity of commercial samples.

10aAndiroba10aMorphoanatomy10aPhytochemical screening10aQuality control10aRutin.1 aLuz, Tássio, Rômulo Si1 aLeite, José, Antonio Co1 aBezerra, Samara, Araújo1 ade Mesquita, Ludmilla, Santos Sil1 aRibeiro, Edilene, Carvalho G1 aDe Mesquita, José, Wilson Car1 aSilveira, Daniella, Patrícia1 aBrito, Maria, Cristiane1 aVilanova, Crisálida, Machado1 aAmaral, Flavia, Maria Mend1 aCoutinho, Denise, Fernandes uhttps://www.phcogres.com/article/2019/11/4/104103prpr4119