02683nas a2200289 4500008004100000245016400041210006900205260001600274300001400290490000700304520175800311653002302069653001602092653001902108653001602127100002202143700001902165700001902184700001602203700001602219700001802235700001902253700002002272700001802292700001702310856006602327 2025 eng d00aExploring the Pharmacological Potential of Achyranthes aspera (Latzeera): A Complete Investigation of its Anticancer, Anti-Microbial and Antioxidant Activities0 aExploring the Pharmacological Potential of Achyranthes aspera La cAugust 2025 a1315-13270 v173 a

Background: A medicinal herb called Achyranthes aspera has been used for centuries to treat a wide range of illnesses. By assessing its antineoplastic, anti-microbial and antioxidant properties. This study sought to thoroughly explore Achyranthes aspera pharmacological potential. Materials and Methods: Antibacterial activity against a panel of bacterial strains was assessed using the disc diffusion method. To ascertain cell viability in cancer cell lines, anti-cancer activity was assessed using the MTT assay. The antioxidant activity of the plant extract was assessed by its capacity to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Results: Achyranthes aspera extract showed encouraging antibacterial efficacy against specific bacterial strains, however not as strong as the common antibiotic, ciprofloxacin. The MTT assay indicated possible anti-cancer efficacy by showing a notable dose-dependent reduction in cancer cell lines' cell viability. Through the scavenging of free radicals, the extract from Achyranthes aspera also demonstrated strong antioxidant activity. Conclusion: The pharmacological potential of Achyranthes aspera is strongly supported by this investigation, confirming its historic use in treating a variety of illnesses. Promising antioxidant, antimicrobial and anti-cancer properties were demonstrated by the plant extract. In order to determine the bioactive components, clarify the underlying mechanisms of action, assess the protection and efficacy of Achyranthes aspera extracts in preclinical, clinical contexts, these findings call for additional research.

10aAchyranthes aspera10aAnti-cancer10aAnti-microbial10aAntioxidant1 aChaudhuri, Arijit1 aDash, Biswajit1 aSarkar, Ashish1 aAlam, Afrin1 aGarg, Ayush1 aDevi, Shivani1 aSharma, Ankita1 aChauhan, Varsha1 aKaur, Tanbeer1 aBawa, Yashna uhttps://www.phcogres.com/article/2025/17/4/105530pres20252314