02563nas a2200241   4500008004100000245015200041210006900193260001400262300001200276490000700288520174500295653001702040653002202057653001702079653002002096653002502116653002602141100002202167700001502189700002302204700002802227856006602255       2025                        eng d00aNatural Marine Species Bioactive Compounds and their Ethnopharmacological Approach from Ecological Biodiversity: Sustainable Therapeutic Properties0 aNatural Marine Species Bioactive Compounds and their Ethnopharma  cJune 2025  a697-7060 v173 a<p class="rtejustify">Marine ecosystems are a rich source of bioactive compounds, offering immense potential for therapeutic applications. Research studies from pubmed, Google scholar, Science direct, databases provided derived from diverse organisms such as algae, sponges, mollusks, and marine microorganisms, these natural products exhibit a wide range of pharmacological properties, including antimicrobial, anti-inflammatory, antioxidant, and anticancer activities. Ethnopharmacological knowledge, deeply rooted in traditional practices, serves as a valuable guide for identifying the medicinal potential of marine resources, creating a bridge between traditional wisdom and modern drug discovery. Recent advancements in biotechnological tools and sustainable bioprospecting have accelerated the discovery, isolation, and development of these bioactive compounds into promising therapeutic agents. Despite these advancements, significant challenges remain. The exploration of marine biodiversity is still limited, with many ecosystems, such as deep-sea and polar regions, largely unexplored. Sustainable harvesting practices, understanding the mechanisms of action and pharmacokinetics of marine bioactive, and mitigating the environmental impacts of large-scale extraction are critical issues. Additionally, the integration of ethnopharmacological knowledge with modern scientific approaches requires systematic validation and documentation. This review emphasizes the therapeutic potential of marine bioactive compounds, highlights the importance of sustainable and ethical bioprospecting practices, and identifies key research gaps that must be addressed to fully harness the benefits of marine biodiversity for global health.</p>
10aBiodiversity10aEthnopharmacology10aMarine drugs10aMarine organism10aMarine Pharmacognosy10aSecondary metabolites1 aGanguly, Paramita1 aSaha, Puja1 aChatterjee, Sandip1 aPati, Prangya, Paramita  uhttps://www.phcogres.com/article/2025/17/3/105530pres20252162