03326nas a2200229 4500008004100000245016400041210007100205260001500276300001000291490000700301520253200308653001302840653002102853653001802874653002102892100002202913700002702935700002602962700001902988700002703007856006203034 2021 eng d00aImmunological, Biochemical, and Infant‑Toddler Quality of Life Parameter‑Based Study of Swarna Prashana (a Herbo‑Mineral Ayurveda Preparation) in Infants0 aImmunological Biochemical and Infant‑Toddler Quality of Life Par cApril 2021 a34-410 v133 a

Background: Increasing rate of emergence of newer infection, resistance to antibiotics, reoccurrence of infections, and malnutrition have created a space for an effective and safe solution of above issues to mankind. Swana Prashana is a unique concept of Indian system of medicine for improving the generalized immunity consequently helping the child to resist and fight against various infection and diseases. Aims: Study was planned to evaluate the efficacy of Swarna Prashana and Swarna Vacha Prashana in infants. Materials and Methods: A randomized, controlled, single-blind clinical study was planned in healthy infants to study the effect of Swarna Prashana in anthropometry, hematological, biochemical, immunological, and infant-toddler quality of life (ITQOL) parameters in 3 differently categorized groups namely Group A: (n = 39, Ghrita and Madhu). Group B: (n = 42, Swarna Bhasma, Ghrita and Madhu) Group C: (n = 38, Swarna Bhasma, Ghrita, Madhu and Vacha Churna). Results: The present clinical study showed statistically highly significant (P < 0.001) increase in all the anthropometrical measurements of infants all three groups. The drugs did not hamper normal growth of the infants and they did not have any additional effect on enhancing the anthropometrical values. Hematological and biological parameters did not show significant difference in comparison in all groups. The results of Renal function and liver function tests were in normal limits after completion of treatment and post treatment follow-up suggestive of safe to be administered in infants. Immunological parameters also did not show significant difference of comparison in all groups except in Group C where immunoglobulin G (IgG), IgM, albumin, globulin levels were increased. Group C significantly improved all the ITQOL parameters while on comparison significant difference was observed in improving the physical abilities only. Conclusion: Current study suggests Swarna Prashana as infants health promotive and morbidity preventive. Author advocates a large scale randomized double blind clinical trial for further validation of impact of Swarna Prashan as mass health-care initiative.

10aAyurveda10aImmunomodulation10aSwarnaprashan10aVyadhi kshamatva1 aRathia, Satyawati1 aChandravanshi, Lowkesh1 aKori, Virendra, Kumar1 aPatel, Kalpana1 aGupta, Prashant, Kumar uhttps://www.phcogres.com/article/2021/13/1/104103prpr6920