@article {1264, title = {Exploring the Logic Behind the Usage of Fresh Drugs in Ayurvedic Formulations through Preliminary Phytochemistry and HPTLC Analysis}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {June 2024}, pages = {549-557}, type = {Original Article}, chapter = {549}, abstract = {

Background: Ayurvedic principles provide guidelines for medicinal herb usage, emphasizing differences in fresh and dried forms. Emphasis is given to the use of doubled quantities of raw drugs when taken in fresh form, focusing on some exceptions like Guduchi (Tinospora cordifolia Linn.), where double quantity is not required even if taken in fresh form. Despite this, practical challenges often favour the prevalent use of dried forms. Objectives: To validate the Ayurvedic principle for drug selection in formulations through preliminary phytochemistry and HPTLC analysis of Tinospora cordifolia Linn., stems and the decoction prepared with fresh and dry samples in different amounts. Materials and Methods: Fresh and dried Tinospora cordifolia Linn., stems were separately extracted with hexane, chloroform, ethyl acetate and methanol using a Soxhlet continuous extraction apparatus. Guduchi decoctions were prepared with dry and fresh drugs in the required quantities and double quantities. Chromatographic studies of these samples were analyzed using HPTLC with specific mobile phases. Results: Preliminary physicochemical analysis provided similar results for fresh and dry samples. HPTLC analysis revealed the presence of more spots in decoction prepared with new samples and the spots were practically identical irrespective of the quantity taken. Analysis of dry Guduchi samples suggests that taking double the required amount in dry form is better. Further, the methanol extracts exhibited more spots, indicating the prevalence of polar compounds. Conclusion: This study enhances our understanding of Ayurvedic drug usage, suggesting using fresh Guduchi samples in decoctions. For dry samples, doubling the quantity is advised for optimal efficacy. It also provides a foundation for further exploration of its medicinal efficacy.

}, keywords = {Fresh and Dry drug selection, Guduchi, HPTLC, Preliminary phytochemistry, Soxlet extraction, Tinospora cordifolia}, doi = {10.5530/pres.16.3.65}, author = {Sree Deepthi GN and Thirupataiah Boini and Praveen Balakrishnan and Krishna Kumar V and Sinimol TP} } @article {1231, title = {Tinospora cordifolia: An Optimistic Herb for Comprehensive Gesundheit}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {April 2024}, pages = {219-229}, type = {Review Article}, chapter = {219}, abstract = {

The necessity for wellness and good habits that boost resistance to illness has come to light due to worries about possible health concerns. Because they are harmless, biologically active polysaccharides derived from plants are excellent substitutes for treating various illnesses. Tinospora cordifolia (Thunb.) Miers, an evergreen perennial climber, is known as "guduchi." This plant, which is dioecious and deciduous, is a member of the Menispermaceae family. In the Indian medical system, a plant named Rasayana is incredibly beneficial. Different extraction and purification techniques have been used to separate and characterise the polysaccharides from Tinospora cordifolia. In addition to hot-water extraction, other state-of-the-art techniques are used to extract the polysaccharides from T. cordifolia, such as Enzyme-Assisted Extraction (EAE), pulsed electric field, microwave-assisted extraction, ultrasound-assisted extraction, and supercritical fluid extraction. The modern healthcare system has also recognised its efficacy. The stem of the plant may be used medicinally. Because the stems contain more alkaloids than the leaves, the entire plant is utilised medicinally. This plant also offers many other benefits, including immunomodulation, hypoglycemia, antioxidants, anti-hyperglycemia, allergies, inflammation, and diabetic mellitus. Most of the plant{\textquoteright}s chemical makeup comprises alkaloids, glycosides, steroids, sesquiterpenoids, aliphatic, diterpenoid lactones, and other unidentified evidence. This study highlights the many traditional and ethnobotanical uses of T. cordifolia and the countless pharmacological, phytochemical, and clinical literature written about the plant.

}, keywords = {Ethnobotanical, Guduchi, Pharmacological., Phytochemical, Polysaccharides, Tinospora cordifolia}, doi = {10.5530/pres.16.2.28}, author = {Snehangshu Gupta and Annammadevi G.S and Sourav Nag and Reshmi Paul and Sumanta Mondal} }