@article {1492, title = {Hedychium spicatum (Shati): A Comprehensive Review of its Pharmacological Activities and Phytochemical Constituents}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {August 2025}, pages = {1183-1186}, type = {Review Article}, chapter = {1183}, abstract = {

Ayurvedic medicine, originating from historical Indian customs, is a comprehensive and revered treatment approach that recognizes the inter-connectedness of the body, mind, and spirit. Hedychium spicatum Buch-Ham (Zingiberaceae), sometimes called spiked ginger lily, is distributed throughout the Himalayan area. The rhizome contains around 4\% essential oil, and its phytochemical analysis has revealed the existence of many terpenoids, including monoterpenoids, sesquiterpenoids, and diterpenoids. The rhizomes of Hedychium spicatum Buch. Ham are conventionally employed for treating pain, inflammation, asthma, respiratory problems, and fevers, tranquilizing, lowering blood pressure, reducing spasms, depressing the central nervous system, alleviating pain, reducing inflammation, acting as an antihistamine, fighting against microbes, acting as an antioxidant, combating fungal infections, eliminating lice, and exhibiting toxic effects on cells. Hedychium spicatum Buch-Ham is a rhizomatous plant utilized in the pharmaceutical, culinary, cosmetic, and fragrance sectors. This review article will provide a concise overview of many features of Hedychium spicatum, including its pharmacological effect and bioactive components.

}, keywords = {Anti-Histaminic, Ayurvedic medicine, Hedychium Spicatum Buch-Ham, Inflammation}, doi = {10.5530/pres.20252217}, author = {Krupa Joshi and Ashimkumar Sen and Dhanya B. Sen and Aarti S. Zanwar and Vatsal Gujariya} } @article {1419, title = {Identification and Quantification of Four Bioactive Markers in Sanjivani Vati Using High-Performance Thin Layer Chromatography}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {April 2025}, pages = {619-626}, type = {Original Article}, chapter = {619}, abstract = {

Background: Sanjivani Vati (SV) is an extensively used multicomponent Ayurvedic medicine, recommended for fever, indigestion, dysentery, gastroenteritis and more. The pharmaceutical standardization of SV and estimation of its tannin and embelin content have been reported in previous studies. However, the identification and quantification of other bioactive constituents namely, aconitine, gallic acid and β-asarone, etc. remain unaddressed. Also, concerns arise regarding one of its ingredients i.e. Vatsanabha (Aconite species), historically recognized as one of the most poisonous plants. It is used after meticulous processing specified in classical texts. Still, it is crucial to identify the amount of aconitine being delivered in the drug to ensure optimal therapeutic benefit while minimizing adverse reactions. In addition, another issue is that Vatsanabha is being sold as a mixture of various species in Indian markets. Previous research has highlighted significant qualitative and quantitative variations in the total alkaloid content among different species of Vatsanabha. Materials and Methods: The present communication deals with identifying and quantifying four bioactive markers viz. Gallic acid, Piperine, β-asarone and Aconitine in SV prepared with two species of Vatsanabha namely Aconitum nepellus L. (SV -1) and Aconitum balfourii Holmes ex Stapf (SV-2) using High-performance Thin Layer Chromatography. Results: Gallic acid, piperine and β-asarone were detected in both SV groups. However, aconitine was not detected in any of the samples. Identification was confirmed by matching the Rf and spectrum overlay. The selected solvent system yielded effective separation from the matrix with an \ value of 0.45{\textpm}0.01 for gallic acid, 0.27{\textpm}0.01 for piperine and 0.62{\textpm}0.01 for β-asarone. The amount of gallic acid was determined to be 1266 μg and 1395 μg in 100 mg of SV1 and SV2 respectively. Piperine was 35.70 μg and 49.95 μg per 100 mg of SV1 and SV2, respectively. β-asarone was 135.3 μg and 236.1 μg in SV1 and SV2 respectively. Conclusion: The concentration of all the detected biomarkers is higher in SV-2 than in SV-1. The presence of these marker compounds helps explain the probable mode of action of SV and offers simple, efficient methods for estimating these biomarkers.

}, keywords = {Aconitine, Ayurvedic medicine, Biomarkers, HPTLC, Sanjivani Vati, Vatsanabha}, doi = {10.5530/pres.20252093}, author = {Shreshtha Kaushik and Nikhil Mehere and Mohit Upadhyay and Pramod Yadav and Pradeep Kumar Prajapati} } @article {1149, title = {A Powerful Molecule of Ayurveda Science}, journal = {Pharmacognosy Research}, volume = {15}, year = {2023}, month = {June 2023}, pages = {455-461}, type = {Review Article}, chapter = {455}, abstract = {

Shilajit is naturally found substance, also termed as shilajatu, salajit, mummiyo, or mimie. It is blackish powder obtained from high mountain rocks, especially in the Himalayans mountains. It has been used by Ayurvedic medicines to cure several disorders and to improve the quality of life. To support its rasayana property, an effort has been made to review shilajit with respect to its origin, variations, physical properties, purification, medicinal properties, and significant biological properties. Shilajit has been demonstrated to offer different health advantages based on the area from where it was harvested. Antioxidant activity and immuno-modulatory activity were highlighted among the many biological characteristics of shilajit since they are strongly related to its rasayana potential. The present review finds the various types and qualities of biomarkers in shilajit which ensure the quality, safety and effectiveness of shilajit.

}, keywords = {Ayurvedic medicine, Bioactives, Shilajit, Traditional medicine.}, doi = {10.5530/pres.15.3.046}, author = {Rubiya Saher Quazi and Venkat Chougule and Mahesh Uttamrao Shinde and Aamer Iqbal Quazi and Shivshankar Malkarjun Gunjegaokar and Amol Arun Joshi} }