@article {1346, title = {Diabetes: Exploring the Intersection of Metabolic Disorders, Lifestyle Factors and Herbal Remedies: A Review}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {January 2025}, pages = {11-17}, type = {Review Article}, chapter = {11}, abstract = {

A chronic metabolic disorder, Diabetes mellitus significantly poses a health challenge globally. The escalating prevalence of diabetes, coupled with concerns regarding the side effects of conventional antidiabetic drugs, has spurred increased interest in exploring alternative therapeutic approaches. Herbal medicines, deeply rooted in traditional healing practices, have emerged as promising candidates for managing diabetes. The objective of this review is to optimise the current scientific literature on herbal medicines employed as antidiabetic agents. The review encompasses an in-depth analysis of diverse medicinal plants which have potential for management of T2DM. The potential of these herbal remedies in improving insulin sensitivity, modulating glucose metabolism and mitigating diabetes-related complications are established. Furthermore, the review critically examines clinical studies evaluating the potency and safe usage of herbal medicines in diabetic populations. Emphasis is placed on highlighting the need for further research and addressing challenges associated with standardization and quality check of herbal preparation. The integration of herbal medicines into mainstream diabetes care is explored, considering the potential for synergistic use with conventional therapies. In nutshell; this review consolidates existing knowledge, sheds light on promising avenues for future research and emphasizes the significance of herbal medicines in the quest for effective, safe and sustainable antidiabetic interventions. The wealth of traditional wisdom encapsulated in these natural remedies presents a valuable resource in the pursuit of novel therapeutic strategies for diabetes management.

}, keywords = {Antidiabetic activity, Diabetes, Herbal plants, Metabolic Disorder, T2DM}, doi = {10.5530/pres.20251951}, url = {https://readarticle.org/lensarticle/diabetes-exploring-the-intersection-of-metabolic-disorders-lifestyle-factors-and-herbal-remedies-a-review/}, author = {Shweta Bhandari and Rahul Trivedi and Rajesh A. Maheshwari and Swetaba Besh and Maitri Mahant and Sapana Patil and Vishal Garg and Ram Singh} } @article {1195, title = {Exploring the Therapeutic Potential of Herbal Plants in Managing Blood Sugar Levels: A Comprehensive Evaluation}, journal = {Pharmacognosy Research}, volume = {16}, year = {2023}, month = {December 2023}, pages = {10-18}, type = {Review Article}, chapter = {10}, abstract = {

Hyperglycemia, characterized by persistently high blood glucose levels due to insufficient insulin release or insulin resistance, is a major global health concern. The World Health Organization (WHO) reports a substantial increase in the number of diabetic patients, from 108 million in 1980 to 422 million in 2014, and further to 463 million in 2020. As a result, there has been a growing demand for medicinal plants to address this issue. Traditional medicine has long recognized and utilized various medicinal herbs with hypoglycemic properties. This review focuses on eight specific medicinal plants: Ficus religiosa (Moraceae), Syzygium cumini (Myrtaceae), Momordica charantia (Cucurbitaceae), Curcuma longa (Zingiberaceae), Ocimum tenuiflorum (Lamiaceae), Morinda citrifolia (Rubiaceae), Trigonella foenum-graecum Linn. (Fabaceae), and Peganum harmala (Zygophyllaceae), which have been found to play a significant role in managing hyperglycemia. The article explores the phytochemical constituents of these plants responsible for their hypoglycemic effects and elucidates their mechanisms of action. By providing a comprehensive review of these medicinal plants, this article offers valuable insights into their potential use for managing hyperglycemia.

}, keywords = {Herbal plants, Hyperglycemia, Insulin resistance, Phytoconstituents, Therapeutic potential.}, doi = {10.5530/pres.16.1.2}, author = {Archita Katrolia and Ved Pal and Vikesh Kumar Shukla and Rohit Singh} } @article {1101, title = {Unravelling the Approaches to Treat Osteoarthritis: A Focus on the Potential of Medicinal Plants}, journal = {Pharmacognosy Research}, volume = {15}, year = {2023}, month = {December 2022}, pages = {13-25}, type = {Review Article}, chapter = {13}, abstract = {

Background: Osteoarthritis (OA) is the most prevalent chronic rheumatic disorder, affecting more women than men. The prevalence and course of OA are increased by ageing and obesity. Numerous other risk factors for OA progression include oxidative stress, injury, mechanical stress, and metabolic problems. Interleukin{\textendash}1 is released during inflammatory responses, which destroys cartilage. Interleukin{\textendash}1 is correlated with the release of proteases, an enzyme that destroys cartilage further. Other cytokines similar to TNF{\textendash}alpha induce the enzyme matrix metalloproteinases (MMP), which causes joint injury. Collagenase is another enzyme that degrades collagen and so impacts negatively on the articular cartilage. NSAIDs, opioid analgesics, topical analgesics, and intra-articular steroids are being used to alleviate osteoarthritis pain, and symptoms. However, various adverse effects are linked with all of these medications, limiting their usage, for example, NSAIDs used to relieve OA pain. Nonetheless, they exhibit gastrointestinal, cardiovascular, and nephrotoxicity. Tramadol also has an effect on the central nervous and gastrointestinal systems. Patients were interested in herbal plants because they were worried about the safety and inadequate effectiveness of pharmaceuticals. Plants have been used to cure a variety of ailments since ancient times, and several plants have the ability to treat OA. According to several studies, the pain and progression of OA may be considerably slowed, or halted by bioactive chemicals found in plants. Conclusion: Here we analysed the current scientific literature available that revealed a rising number of research on the possible antiosteoarthritic effects of medicinal plants and their principal ingredients, indicating the possibility of a novel therapeutic use.

}, keywords = {Antiosteoarthritic, Cartilage, Chondrocytes, Collagenase., Herbal plants, Inflammation}, doi = {10.5530/097484900001}, author = {Sonali Verma and Sumeet Gupta and Rina Das and Kavita Munjal and Meenakshi Dhanawat and Dinesh Kumar Mehta and Gurudev Goyal and Anshu Gupta} }