@article {1433, title = {Extraction and Quantification of Allicin: A Bioactive Component of Allium sativum}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {June 2025}, pages = {728-739}, type = {Review Article}, chapter = {728}, abstract = {

Allicin, a bioactive compound found in garlic, exhibits remarkable pharmacological properties such as antimicrobial, antioxidant, and anticancer effects. Its therapeutic potential has garnered substantial attention, leading to efforts to refine extraction and quantification methods for precise analysis in garlic-based products. This review examines advanced techniques for allicin extraction from garlic, including Ultrasonic-Assisted Extraction (UAE), Supercritical Water Extraction (SCWE), and Microwave-Assisted Extraction (MAE). UAE employs ultrasonic waves to improve mass transfer and solvent penetration, optimizing allicin yield while reducing extraction time. SCWE utilizes the unique properties of water above its critical point to extract allicin efficiently and selectively, providing an eco-friendly alternative. MAE uses microwave energy to rapidly heat solvents, enhancing allicin extraction through improved penetration and dissolution. Alongside these extraction methods, this review highlights analytical techniques for allicin quantification, including High-Performance Liquid Chromatography (HPLC), High-Performance Thin-Layer Chromatography (HPTLC), and Ultraviolet (UV) spectroscopy. HPLC offers exceptional sensitivity and specificity for splitting and measuring allicin in complex matrices, making it invaluable for accurate pharmacokinetic studies and quality control of pharmaceutical formulations. HPTLC offers quick screening with minimal sample preparation, ideal for routine investigation and batch testing of garlic extracts. UV spectroscopy, a cost-effective technique, detects allicin through its characteristic absorption spectra, enabling quick evaluations of garlic product quality and stability. This review consolidates recent advancements in allicin extraction and quantification techniques, emphasizing their applications in the pharmaceutical, nutraceutical, and food sectors. Future research aims to optimize extraction parameters to maximize allicin yield and develop robust analytical methods to address the growing demand for quality assurance and therapeutic efficacy in garlic-based products.

}, keywords = {Allicin, Extraction, Garlic, Quantification}, doi = {10.5530/pres.20252211}, author = {Dhanya B. Sen and Deven K. Parmar and Ashim Kumar Sen and Rajesh A. Maheshwari and Aarti S. Zanwar and Krupa Joshi and Shaileshkumar K. Koradia} } @article {1492, title = {Hedychium spicatum (Shati): A Comprehensive Review of its Pharmacological Activities and Phytochemical Constituents}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {August 2025}, pages = {1-4}, type = {Review Article}, chapter = {1}, abstract = {

Ayurvedic medicine, originating from historical Indian customs, is a comprehensive and revered treatment approach that recognizes the inter-connectedness of the body, mind, and spirit. Hedychium spicatum Buch-Ham (Zingiberaceae), sometimes called spiked ginger lily, is distributed throughout the Himalayan area. The rhizome contains around 4\% essential oil, and its phytochemical analysis has revealed the existence of many terpenoids, including monoterpenoids, sesquiterpenoids, and diterpenoids. The rhizomes of Hedychium spicatum Buch. Ham are conventionally employed for treating pain, inflammation, asthma, respiratory problems, and fevers, tranquilizing, lowering blood pressure, reducing spasms, depressing the central nervous system, alleviating pain, reducing inflammation, acting as an antihistamine, fighting against microbes, acting as an antioxidant, combating fungal infections, eliminating lice, and exhibiting toxic effects on cells. Hedychium spicatum Buch-Ham is a rhizomatous plant utilized in the pharmaceutical, culinary, cosmetic, and fragrance sectors. This review article will provide a concise overview of many features of Hedychium spicatum, including its pharmacological effect and bioactive components.

}, keywords = {Anti-Histaminic, Ayurvedic medicine, Hedychium Spicatum Buch-Ham, Inflammation}, doi = {10.5530/pres.20252217}, author = {Krupa Joshi and Ashimkumar Sen and Dhanya B. Sen and Aarti S. Zanwar and Vatsal Gujariya} }