@article {1431, title = {In silico Insights Into the Medicinal Potential of Phyllanthus amarus: Phytoconstituents and Therapeutic Applications}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {June 2025}, pages = {707-718}, type = {Review Article}, chapter = {707}, abstract = {

Phyllanthus amarus is a globally distributed herb. Over the 3000 years, it has been used as traditional medicine. This plant is articulated in different languages differently like in Hindi- Bhuyiavla, Jangli amla, Marathi- Bhuivali, Bihari- Muikoa, Sanskrit- Bhumyaamlaki, etc. It is an herb that can grow between 30 and 75 cm tall annually. Worldwide, Phyllanthus amarus is a plant widely distributed in tropical and subtropical areas. In Indian Ayurveda, the Phyllanthus amarus is used as a traditional medicine. It treats various diseases such as cough, diuretics, menstrual problems, stomach, kidney, etc. Scientific research said that Phyllanthus amarus exhibits potency against multiple diseases including diabetes, arthritis, inflammation, convulsion, neuroactive, hepatoprotective, nephroprotective, vasoconstriction, etc. Phyllanthus amarus has several secondary metabolites such as tannin, flavonoid, saponin, alkaloids, terpenoids, lignans, sterols, and volatile oils. Aqueous and non-aqueous extraction of Phyllanthus amarus and isolation of chemical compounds such as securinine, phyllanthine, rutin, quercitrin, amariin, geraniin, hypophyllanthins, isonirtetralin, amarosterol-A, phytol, phenazine, ursolic-acid, isolintetralin, etc. These compounds are responsible for pharmacological activity such as anti-cancer, antibacterial, analgesic, antifungal, antioxidant, antiviral, contraceptive, anti-inflammatory, etc. On the other hand, molecular docking is a potent computational process for studying molecular interactions from the drug discovery perspective. It is applied to forecast the orientation in which small drug molecules will bind to their protein targets, predicting their affinity and activity.

}, keywords = {Medicinal potential, Molecular docking, Phyllanthus amarus, Phytoconstituent}, doi = {10.5530/pres.20252168}, author = {Ayushi Varshney and Pawan Kumar Gupta and Prashant Kumar and Shashi Bhooshan Tiwari} } @article {1510, title = {Phytochemical and Pharmacological Properties of Tinospora cordifolia (Giloy)}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {September 2025}, pages = {1171-1182}, type = {Review Article}, chapter = {1171}, abstract = {

Tinospora cordifolia (commonly known as Giloy or Guduchi) is a revered herb in traditional Ayurvedic medicine, widely recognized for its rejuvenating properties. The plant{\textquoteright}s therapeutic effects stem from a rich profile of phytochemicals-alkaloids, terpenoids, lactones, and polysaccharides-responsible for diverse pharmacological activities such as immunomodulation, antioxidant, anti-inflammatory, antidiabetic, antimicrobial, and hepatoprotective effects. This paper explores the phytochemical constituents, pharmacological potentials, and clinical relevance of T. cordifolia, with a focus on its mechanisms of action and its growing role in integrative medicine, particularly post-COVID-19. The review also highlights the necessity of more rigorous scientific studies and standardization to bridge traditional uses and modern therapeutic applications.

}, keywords = {Anti-inflammatory of Giloy, COVID-19 Adjunct Therapy, Giloy, Immunomodulatory Activity of Giloy, Pharmacological Properties of Giloy, Tinospora cordifolia}, doi = {10.5530/pres.20252350}, author = {Richa Kothari and Manoj Kumar Bajhaiya and Shefali Soni and Abhishek Kumar and Samreen Ali and Ankit Rajput and Prashant Kumar and Sagar Shrotriya and Kanchan Thakur} } @article {1382, title = {Phytopharmacological Insights into Ricinus communis: A Comprehensive Overview}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {April 2025}, pages = {348-357}, type = {Review Article }, chapter = {348}, abstract = {

Medicinal plants are used in the traditional medicinal system and in Ayurveda globally. Euphorbiaceae is a large family which contains more than 3000 species. Ricinus communis or castor bean plant is well-known plant of Ayurveda. The herbal and natural medicines are the cost-effective and they have lesser side effects than currently available medicines in the market. Ricinus communis has many phytoconstituents such as ricinine, ricin A, ricin B, ricin C, ricinoleic acid, Y-sitosterol, fucosterol, stigmasterol, ricinus agglutin etc. which are responsible for various pharmacological activities. Traditionally, it has various pharmacological properties such as antioxidant activity, antifertility activity, antiulcer activity, antidiabetic activity, antimicrobial activity, hepatoprotective activity, immunomodulatory activity, bone regeneration activity, cytotoxic activity, anti-inflammatory activity etc. They also exhibited free radical scavenging potential along with repellent properties. The main objective of this review is to reveal all updated information{\textquoteright}s like phytochemicals, pharmacological activities of Ricinus communis by scientific evidences.

}, keywords = {Herbal Medicines, Medicinal plants, Pharmacological activities, Phytochemicals, Ricinus communis}, doi = {10.5530/pres.20251940}, author = {Surya Nath Pandey and Prashant Kumar and Harishchandra Verma and Sumit Durgapal and Balwan Singh} }