@article {1431, title = {In silico Insights Into the Medicinal Potential of Phyllanthus amarus: Phytoconstituents and Therapeutic Applications}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {June 2025}, pages = {707-718}, type = {Review Article}, chapter = {707}, abstract = {

Phyllanthus amarus is a globally distributed herb. Over the 3000 years, it has been used as traditional medicine. This plant is articulated in different languages differently like in Hindi- Bhuyiavla, Jangli amla, Marathi- Bhuivali, Bihari- Muikoa, Sanskrit- Bhumyaamlaki, etc. It is an herb that can grow between 30 and 75 cm tall annually. Worldwide, Phyllanthus amarus is a plant widely distributed in tropical and subtropical areas. In Indian Ayurveda, the Phyllanthus amarus is used as a traditional medicine. It treats various diseases such as cough, diuretics, menstrual problems, stomach, kidney, etc. Scientific research said that Phyllanthus amarus exhibits potency against multiple diseases including diabetes, arthritis, inflammation, convulsion, neuroactive, hepatoprotective, nephroprotective, vasoconstriction, etc. Phyllanthus amarus has several secondary metabolites such as tannin, flavonoid, saponin, alkaloids, terpenoids, lignans, sterols, and volatile oils. Aqueous and non-aqueous extraction of Phyllanthus amarus and isolation of chemical compounds such as securinine, phyllanthine, rutin, quercitrin, amariin, geraniin, hypophyllanthins, isonirtetralin, amarosterol-A, phytol, phenazine, ursolic-acid, isolintetralin, etc. These compounds are responsible for pharmacological activity such as anti-cancer, antibacterial, analgesic, antifungal, antioxidant, antiviral, contraceptive, anti-inflammatory, etc. On the other hand, molecular docking is a potent computational process for studying molecular interactions from the drug discovery perspective. It is applied to forecast the orientation in which small drug molecules will bind to their protein targets, predicting their affinity and activity.

}, keywords = {Medicinal potential, Molecular docking, Phyllanthus amarus, Phytoconstituent}, doi = {10.5530/pres.20252168}, author = {Ayushi Varshney and Pawan Kumar Gupta and Prashant Kumar and Shashi Bhooshan Tiwari} } @article {1382, title = {Phytopharmacological Insights into Ricinus communis: A Comprehensive Overview}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {April 2025}, pages = {348-357}, type = {Review Article }, chapter = {348}, abstract = {

Medicinal plants are used in the traditional medicinal system and in Ayurveda globally. Euphorbiaceae is a large family which contains more than 3000 species. Ricinus communis or castor bean plant is well-known plant of Ayurveda. The herbal and natural medicines are the cost-effective and they have lesser side effects than currently available medicines in the market. Ricinus communis has many phytoconstituents such as ricinine, ricin A, ricin B, ricin C, ricinoleic acid, Y-sitosterol, fucosterol, stigmasterol, ricinus agglutin etc. which are responsible for various pharmacological activities. Traditionally, it has various pharmacological properties such as antioxidant activity, antifertility activity, antiulcer activity, antidiabetic activity, antimicrobial activity, hepatoprotective activity, immunomodulatory activity, bone regeneration activity, cytotoxic activity, anti-inflammatory activity etc. They also exhibited free radical scavenging potential along with repellent properties. The main objective of this review is to reveal all updated information{\textquoteright}s like phytochemicals, pharmacological activities of Ricinus communis by scientific evidences.

}, keywords = {Herbal Medicines, Medicinal plants, Pharmacological activities, Phytochemicals, Ricinus communis}, doi = {10.5530/pres.20251940}, author = {Surya Nath Pandey and Prashant Kumar and Harishchandra Verma and Sumit Durgapal and Balwan Singh} }