@article {1260, title = {Pharmacognostical Studies on Seeds of Argyreia nervosa (Burm. F.) Boj. and its Market Adulteration Thespesia populnea (L.) Sol. Ex Corr{\^e}a}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {June 2024}, pages = {495-507}, type = {Original Article}, chapter = {495}, abstract = {

Background: The seeds of Argyreia nervosa (Burm.f.) Boj. (Syn.: A. speciosa (L.f.) Sweet., Convolvulaceae) is the source of Vriddhadaru of Ayurveda and Samudrappachai of Siddha. The seeds are used in Indian systems of medicine for rejuvenating, as an aphrodisiac, hypotensive, spasmolytic, antidiabetic, antiviral, antifertility, antibacterial and diuretic drug. The dried seeds of Thespesia populnea (L.) Sol. ex Corr{\^e}a (Malvaceae) is Parisha/Kapitana according to Ayurveda and Puvarasu in Siddha. The latter is used instead of seeds of A. nervosa due to similar appearance. Objectives: A comparative study has been executed to identify the official source drugs by carrying out Pharmacognostical studies, for dried seeds of A. nervosa and T. populnea. Materials and Methods: The Macro-microscopic characterization and TLC/HPTLC profiling were carried out by appropriate methods published by standard books/Pharmacopoeias. Results: Observations were documented comparatively so that surface characters of testa and embryo; transverse section of testa, cotyledon, radicle and powder microscopy can be used as diagnostic features to differentiate the two sources. The TLC/HPTLC profile of ethanolic extract of two species provides a suitable method for monitoring identity, purity and also standardisation of these drugs in formulations. Conclusion: The results will help in differentiating these plant drugs and authentication/identification of the crude drug/raw drug standardization of the single drug or as a powder form, even when added to a formulation these drugs containing as ingredients.

}, keywords = {Baby wood-rose, Market adulteration, Powder microscopy, Seed anatomy, Vriddhadaru}, doi = {10.5530/pres.16.3.60}, author = {Sundharamoorthy Susikumar and Govindarajan Nartunai and Koppala Narayanan Sunil Kumar and Thatipelli Sujith and Ramachandran Shakila and Raju Ilavarasan} } @article {1263, title = {Standardization of Madhumukthi Kudineer Chooranum Using Pharmacognostic, Physicochemical and HPTLC Studies}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {June 2024}, pages = {531-539}, type = {Original Article}, chapter = {531}, abstract = {

Background: Siddha system of medicine is considered to be foremost among other systems of medicine. Many medicines are available in traditional systems for all kind of diseases. Most people show their interest towards Siddha medicine for non-communicable diseases especially for diabetes, hypertension, etc., Poly herbal formulations like Avarai kudineer has been authorized for prescription for Madhumegam. Madhumukthi Kudineer Chooranum (MKC) is one such medicine which has been found efficacious in Madhumegam (Diabetes mellitus). The current study is aimed at standardizing MKC employing pharmacognostic and chemical analyses with the aim of developing standards for quality control of this important medicine of Siddha. Materials and Methods: MKC was analyzed for pharmacognostic, physiochemical and HPTLC standards following standard procedures mentioned in Pharmacopoeias. Results: Macroscopy, powder microscopy was matched with the characters of these ingredients as reported in pharmacopoeias. The physicochemical standards were correlated with standards. TLC of MKC showed 10 spots under UV 254 nm, 13 spots under UV 366 nm and after spray with 5\% vanillin sulphuric acid solution. Conclusion: The reported results will be supportive for standardization and future studies of MKC.

}, keywords = {Antidiabetic, Antioxidant, Kudineer chooranum, Madhumegam, Polyherbal formulation}, doi = {10.5530/pres.16.3.63}, author = {Rajamanickam Baskar and Govindaraju Bharathkumar and Koppala Narayana Sunil Kumar and Ramachandran Shakila and Manekshah Yovas Rajammal and Sikkal Selvaraaju Selvapriya and Thangarasu Hema Devi} }