@article {1416, title = {A Comprehensive Review on Medicinal Herbal Plant with Potential Hypolipidemic Activity}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {April 2025}, pages = {489-506}, type = {Review Article}, chapter = {489}, abstract = {

Hyperlipidaemia, characterized by elevated blood lipid levels, is a significant risk factor for cardiovascular diseases. While traditional pharmacological treatments are available, their effectiveness and potential side effects highlight the need to explore alternative approaches. Herbal plants have attracted attention due to their variety of bioactive compounds with therapeutic potential. This review aims to provide an overview of the lipid-lowering effects of several herbal plants, discussing their mechanisms of action and available clinical evidence. Notable herbs such as garlic (Allium sativum), ginger (Zingiber officinale) and green tea (Camellia sinensis) have shown potential in reducing lipid levels by modulating enzymes involved in lipid metabolism, inhibiting cholesterol absorption and enhancing lipid excretion. The findings suggest that numerous phytochemicals may offer therapeutic benefits for managing hyperlipidaemia. In addition, an analysis of 83 compounds indicates that 60 adhere to Lipinski{\textquoteright}s Rule of Five and Veber{\textquoteright}s Rule, suggesting that these compounds possess optimal physicochemical properties, which could make them viable candidates for future treatments of hyperlipidaemia.

}, keywords = {Herbal drug, Herbal medicine, Hyperlipidaemia Activity, Lipid Herb Drug Interaction, Lipinski{\textquoteright}s Rule, Physicochemical properties, Veber{\textquoteright}s Rule}, doi = {10.5530/pres.20252009}, author = {Devendra Dhanorya and Vikas Pnadey and Rajesh Shukla and Yuvraj Vishwakarma and Gourav Kumar Bairagi and Vandana Gupta and Pushpender Bardiya and Shivam Kumar Kori and Priyansh Patel and Nishant Kumar Bardiya and Shikha Bhalla and Shubham Anand} } @article {1413, title = {Unveiling the Phytochemical Profile and Therapeutic Benefits of Solanum xanthocarpum: A Systematic Review}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {April 2025}, pages = {440-451}, type = {Review Article}, chapter = {440}, abstract = {

Solanum xanthocarpum, a significant medicinal plant in traditional systems of medicine, possesses a rich phytochemical profile that contributes to its diverse therapeutic applications. This review explores the bioactive compounds such as alkaloids, flavonoids, and glycosides, which are responsible for the plant{\textquoteright}s pharmacological properties, including antioxidant, anti-inflammatory, antimicrobial, and antihyperglycemic activities. Recent studies have also highlighted its potential in treating respiratory disorders, liver dysfunction, and microbial infections. By consolidating traditional uses with modern pharmacological research, this paper aims to provide a comprehensive understanding of Solanum xanthocarpum, emphasizing its potential for future therapeutic developments.

}, keywords = {Anti-inflammatory effects, Anti-microbial activity, Antioxidant properties, Ethno-medicine of Solanum xanthocarpum, Phytochemical profile of Solanum xanthocarpum, Therapeutic benefits of Solanum xanthocarpum}, doi = {10.5530/pres.20252059}, author = {Nem Kumar Jain and Shubham Anand and Priyanka Kesari and Rekha Rani and Santosh Kumar and Akanksha Tiwari and Moti Lal and Devendra Dhanorya and Aman Sharma and Sakshi Singh and Manoj Kumar Bajhaiya} } @article {1257, title = {A Comprehensive Review of Ethnomedicinal, Phytochemical and Pharmacological Activity Profile of Achyranthes aspera}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {June 2024}, pages = {472-482}, type = {Review Article}, chapter = {472}, abstract = {

For centuries, humans have harnessed the healing properties of plants to address diverse health conditions. Ancient systems like Ayurveda and Unani medicine hold a rich repository of knowledge extolling the virtues of herbal remedies. Achyranthes aspera, one prolific native herbaceous plant in the South America, Asia and Africa often prospers as one common weed. Its many applications in traditional medicine for treating various diseases are at the heart of this global research. Achyranthes aspera is diverse many chemical ingredients, including terpenoids, alkaloids, steroids, saponins and flavonoids. This paper provides a thorough examination and elucidation of the phytochemical composition across different parts of Achyranthes aspera, delving into its traditional uses and expounding upon its pharmacological properties.

}, keywords = {Achyranthes aspera, Anti- microbial activity, anti-inflammatory activity, anti-oxidant, Antidiabetic activity}, doi = {10.5530/pres.16.3.57}, author = {Nem Kumar Jain and Shubham Anand and Priyanka Keshri and Santosh Kumar and Akshay Singh Sengar and Manoj Kumar Bajhaiya and Devendra Dhanorya and Sapna Yadav and Hema Katra and Sajal Mishra} } @article {1219, title = {A Comprehensive Review of Therapeutical and Ethnobotanical Aspects, Phytoconstituent and Pharmacological Activity of Aesculus indica}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {April 2024}, pages = {203-210}, type = {Review Article}, chapter = {203}, abstract = {

Aesculus indica Wall. Ex Camb. Hook, a member of the Hippocastanaceae family, exhibits robust growth in colder climates worldwide, showcasing its remarkable adaptability. Within its various components lie a diverse array of constituents, each harboring a treasury of advantageous compounds that have found utility across a spectrum of applications. These applications encompass the amelioration of gastrointestinal disturbances, facilitation of hemostasis, management of diabetes, and mitigation of various dermatological afflictions. Through a comprehensive synthesis of information gleaned from an array of authoritative sources including meticulous literature surveys, our study provides a thorough dissection. It traverses the multifaceted tapestry of this plant{\textquoteright}s applications, devlopes into its intricate chemical composition, and elucidates its nuanced effects on human health and well-being. This compendium stands as an invaluable reservoir, poised to aid and embolden scientists and researchers engaged in the exploration of natural products. Its content, meticulously aggregated and meticulously crafted, promises a resourceful springboard for their scholarly inquiries while assuring originality and authenticity in their pursuits.

}, keywords = {Aesculus indica, Anti-diabetic activite, Antimicrobial activity., Antioxidant, Pharmacognosy, Pharmacology activity, Phytochemistry}, doi = {10.5530/pres.16.2.26}, author = {Shubham Anand and Arijit Chaudhuri and Neha Chopra and Devendra Dhanorya and Manoj Kumar Bajhaiya and Gujjala Sai Sri Harsha and Vijeta Bhattacharya and Udichi Kataria and Gaurav Kumar} } @article {1210, title = {Development and Evaluation of Nephroprotective Polyherbal Formulation against Methotrexate Induced Toxicity in Sprague Dawley Rat}, journal = {Pharmacognosy Research}, volume = {16}, year = {2023}, month = {December 2023}, pages = {140-145}, type = {Original Article}, chapter = {140}, abstract = {

Methotrexate (MTX) is one of the most broadly used anti-cancer derivative of aminopterin and it is a first folic acid antagonist. Adult cancer, various malignancies, multiple sclerosis, dermatomyositis, sarcoidosis, psoriasis, rheumatoid arthritis, and severe inflammatory disorders are all commonly treated with MTX. Medicinal plants and herbs contribute, wide range of treatment and prevention from several diseases. Herbal formulations mean dosage form consisting of one or more plants prepared herbs in selected quantities to cure mitigate diseases, by treatment, prevention and sometimes use as a supplement. Petrida foetida is used as traditionally diarrhea, stomach ache and nutritional supplement etc. Vitis vinifera, the fruit is used for dietary and the leaves and seeds are used as several herbal therapy. The current study had carried out to evaluate the nephroprotective activity of leaves and seed extracts of Petrida foetida and Vetis venifera. Nephroprotective activities of ethanolic and aqueous extracts of Petrida foetida and Vitis vinifera seeds were examined against methotrexate induced Kidney damage in Sprague Dawley Rats. Biochemical parameter evaluates like Urea, Creatinine, Uric acid, Blood urea nitrogen, total protein like albumin, globulin was analyzed. Petrida foetida and Vitis venifera seeds extract of exhibited significant (p\<0.05) nephroprotective activity. Ethanolic seeds extract of Vitis vinifera and Petrida foetida menifest moderate activity upon Methotrexate induced Rat models. Study outcome shows the traditional-ethno medicinal use of Methotrexate as a potential source of Nephroprotective activity.

}, keywords = {Blood Urea Nitrogen (BUN)., Creatinine, Methotrexate (MTX), Nephroprotective activity, Polyherbal formulation (PHF)}, doi = {10.5530/pres.16.1.17}, author = {Arijit Chaudhuri and Udichi Kataria and Subodh Kumar Dubey and Neha Chopra and Devendra Dhanorya and Kamal Shah and Nagendra Singh Chauhan} }