@article {733, title = {Bioactivity of Syzygium Jambos Methanolic Extracts: Antibacterial Activity and Toxicity}, journal = {Pharmacognosy Research}, volume = {2}, year = {2010}, month = {March 2010}, pages = {4-9}, type = {Original Article}, chapter = {4}, abstract = {

Methanol extracts from S. jambos leaves were tested for antimicrobial activity and toxicity. S. jambos leaf extract inhibited the growth of 4 of the 14 bacteria tested (29\%). Both gram-positive and gram-negative bacterial growths were inhibited by S. jambos leaf extract, although gram-positive bacteria appeared more susceptible. Two of the 10 gram-negative bacteria (20\%) and 2 of the 4 gram-positive bacteria (50\%) tested had their growths inhibited by the extract. The leaf extract also proved to be toxic in the Artemia franciscana bioassay, with a 48-h LC 50 of 387.9 {\textpm} 38.8 {\textmu}g/mL, making it slightly more toxic than Mevinphos (505.3{\textpm} 37.7 {\textmu}g/mL) and approximately 5-fold less toxic than potassium dichromate (80.4 {\textpm} 4.3 {\textmu}g/mL). Whilst potassium dichromate{\textquoteright}s LC 50 remained constant across the 72-hour test period (24-h LC 50 , 86.3 {\textpm} 5.1; 72-h LC 50 , 77.9 {\textpm} 4.9), the extract and Mevinphos LC 50 values decreased by 72 hours (87.0 {\textpm} 11.3 {\textmu}g/mL and 103.9 {\textpm} 12.8 {\textmu}g/mL, respectively), indicating their similar levels of toxicity in the assay.

}, keywords = {Antibacterial, Medicinal plants, Methanolic extracts, Phytotoxicity, Rose apple, Syzygium jambos}, doi = {10.4103/0974-8490.60577}, author = {S Mohanty and IE Cock} }