@article {562, title = {Gas Chromatography Mass Spectrometry Profiling in Methanolic and Ethyl-acetate Root and Stem Extract of Corbichonia decumbens (Forssk.) Exell from Thar Desert of Rajasthan, India}, journal = {Pharmacognosy Research}, volume = {9}, year = {2017}, month = {December 2017}, pages = {s48-s52}, type = {Original Article}, chapter = {s48}, abstract = {

Background: Corbichonia decumbens (Forssk.) Exell (Molluginaceae), recently has moved to Lophiocarpaceae as per angiospermic plant group (APG) III system, is an annual or short-lived, dwarf, glabrous subshrub, prefers to grow on rocky places and on sand-stones in dry, hot areas of Rajasthan. This is the potential plant with medicinal properties. Vegetative organs under study show antioxidant, anti-inflammatory, antiulcer, antimicrobial, and antinociception activity. Objective: This study was carried out to identify the phytoconstituents present in the methanolic and ethyl-acetate extract of root and stem of C. decumbens by GC-MS analysis. Materials and Methods: Powdered test samples were sequentially extracted with methanol and ethyl-acetate. The compounds obtained as a result of GC-MS screening were identified on the basis of their retention time, peak area and compared with that of literature available and by interpretation of mass spectra. Results: GC-MS analysis of a methanolic extract of root detected mome-inositol (49.53\%), guanosine (20.91\%), and cis-vaccenic acid (9.25\%). While ethyl-acetate extract of root analyzed pentadecanoic acid (17.91\%), octadecanoic acid (15.01\%) and cis-vaccenic acid (12.04\%). Methanolic extract of stem detected mome-inositol (75.47\%), pentadecanoic acid (6.04\%), and 7-tetradecenal, (Z) (4.54\%) while ethyl-acetate extract of stem revealed the presence of 1-heptacosanol (17.35\%), hexadecanoic acid (17.17\%), and octadecanal (12.64\%). Conclusion: The results suggest that C. decumbens (Forssk.) Exell is a plant of potential medicinal value, yielding various bioactive compounds that confirm the application of this plant as a plant-based drug in pharmacy-industry.

}, keywords = {Bioactive compounds, Corbichonia decumbens, Gas chromatography mass spectrometry screening, Lophiocarpaceae, Phytochemical screening, Retention time}, doi = {10.4103/pr.pr_62_17}, author = {Sunita Arora and Manju Saini} }