@article {532, title = {Alpha-amylase inhibitory activity and sterol composition of the marine algae, Sargassum glaucescens}, journal = {Pharmacognosy Research}, volume = {7}, year = {2015}, month = {October 2015}, pages = {314-321}, type = {Original Article}, chapter = {314}, abstract = {

Background: Sargassum species (phaeophyceae) are economically important brown algae in southern parts of Iran. Sargassum is mainly harvested as a row material in alginate production industries and is a source of plant foods or plant bio-stimulants even a component of animal foods. Objectives: In this study, Sargassum glaucescens, collected from the seashore of Chabahar, was employed for phytochemical and biological evaluations. Materials and Methods: For that purpose, the dried algae was extracted by methanol and subjected to different chromatographic separation methods. Results: Six sterols, fucosterol (1), 24(S)-hydroxy-24-vinylcholesterol (2), 24(R)-hydroxy-24-vinylcholesterol (3), stigmasterol (4), β-sitosterol (5) and cholesterol (6) were identified by spectroscopic methods including 1H-NMR, 13C-NMR and mass spectroscopy. In vitro alpha-amylase inhibitory test was performed on the methanolic extract and the results revealed a potent inhibition (IC50 = 8.9 {\textpm} 2.4 mg/mL) of the enzyme compared to acarbose as a positive control. Conclusion: Various biological activities and distribution of sterols in Sargassum genus have been critically reviewed here. The results concluded that these algae are a good candidate for further anti-diabetic investigations in animals and human.

}, keywords = {Alpha-amylase inhibitor, Brown algae, Sargassum glaucescens, Sterol.}, doi = {10.4103/0974-8490.167893}, author = {Nasrin Payghami and Shahla Jamili and Abdolhossein Rustaiyan and Soodabeh Saeidnia and Marjan Nikan and Ahmad Reza Gohari} } @article {769, title = {Chemical Composition and Antimicrobial Activity of Artemisia tschernieviana Besser from Iran}, journal = {Pharmacognosy Research}, volume = {1}, year = {2009}, month = {January 2010 }, pages = {120-124}, type = {Original Article}, chapter = {120}, abstract = {

The oil obtained from hydrodistillation of the aerial parts of Artemisia tschernieviana was analyzed by GC and GC/MS. The main constituents of the 30 identified components were p-cymene (21.3\%), {\textquoteright}-pinene (17.8\%), *-pinene (9.4\%), --terpinene (9.1\%), (Z)-cis-ocimene (8.8\%), and *-cadinol (8.1\%). This species is rich in monoterpenes. Antimicrobial activity was determined against six bacterial strains and one fungal strain. The results show that this oil is active against all the tested strains.

}, keywords = {Artemisia tschernieviana Besser; Essential oil; Antimicrobial activity; p-cymene; {\textquoteright}-pinene; *-pinene; --terpinene; (Z)-beta-ocimene; *-cadinol}, doi = {Nil}, author = {Masoud Kazemi and Mohammad Dakhili and Abdolhossein Rustaiyan and Kambiz Larijani and Mohammad Ali Ahmadi and Valiolah Mozaffarian} }