@article {1260, title = {Pharmacognostical Studies on Seeds of Argyreia nervosa (Burm. F.) Boj. and its Market Adulteration Thespesia populnea (L.) Sol. Ex Corr{\^e}a}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {June 2024}, pages = {495-507}, type = {Original Article}, chapter = {495}, abstract = {

Background: The seeds of Argyreia nervosa (Burm.f.) Boj. (Syn.: A. speciosa (L.f.) Sweet., Convolvulaceae) is the source of Vriddhadaru of Ayurveda and Samudrappachai of Siddha. The seeds are used in Indian systems of medicine for rejuvenating, as an aphrodisiac, hypotensive, spasmolytic, antidiabetic, antiviral, antifertility, antibacterial and diuretic drug. The dried seeds of Thespesia populnea (L.) Sol. ex Corr{\^e}a (Malvaceae) is Parisha/Kapitana according to Ayurveda and Puvarasu in Siddha. The latter is used instead of seeds of A. nervosa due to similar appearance. Objectives: A comparative study has been executed to identify the official source drugs by carrying out Pharmacognostical studies, for dried seeds of A. nervosa and T. populnea. Materials and Methods: The Macro-microscopic characterization and TLC/HPTLC profiling were carried out by appropriate methods published by standard books/Pharmacopoeias. Results: Observations were documented comparatively so that surface characters of testa and embryo; transverse section of testa, cotyledon, radicle and powder microscopy can be used as diagnostic features to differentiate the two sources. The TLC/HPTLC profile of ethanolic extract of two species provides a suitable method for monitoring identity, purity and also standardisation of these drugs in formulations. Conclusion: The results will help in differentiating these plant drugs and authentication/identification of the crude drug/raw drug standardization of the single drug or as a powder form, even when added to a formulation these drugs containing as ingredients.

}, keywords = {Baby wood-rose, Market adulteration, Powder microscopy, Seed anatomy, Vriddhadaru}, doi = {10.5530/pres.16.3.60}, author = {Sundharamoorthy Susikumar and Govindarajan Nartunai and Koppala Narayanan Sunil Kumar and Thatipelli Sujith and Ramachandran Shakila and Raju Ilavarasan} } @article {481, title = {Ulcer Protective Activity of Jatropha gossypiifolia Linn. in Wistar Rats}, journal = {Pharmacognosy Research}, volume = {8}, year = {2016}, month = {March 2016}, pages = {61-66}, type = {Original Article}, chapter = {61}, abstract = {

Background: Several synthetic drugs are useful in the treatment of peptic ulcer, but almost of these drugs are used in prolonging time, it may cause several adverse reactions. However, the herbal medicines are more potent to the treatment and minimize the side effects. Objective: To evaluate the methanol extract of Jatropha gossypiifolia Linn. (MEJG) for gastro protective activity against Wistar rats. Materials and Methods: Anti-ulcer potency of MEJG (100 and 200 mg/kg, b.w.) was assessed using aspirin (200 mg/kg, p.o.) plus pylorus ligation ulcer model and the parameters studied were ulcer index (UI), gastric juice volume, pH, total acidity, and total acid output. Same extract was studied by ethanol-induced (80\%, 5 mL/kg, intragastrically) ulcer model, and the UI and biochemical parameters were studied. Results: The oral administration of MEJG (100 and 200 mg/kg) significantly (P \< 0.001) attenuated the ulcer score and anti-secretary parameters (such as the volume of gastric content, free acidity, total acidity, and total acid output) in the aspirin plus pylorus ligation rats. The extract also significantly attenuated (P \< 0.001) ulcer score in ethanol-induced ulcer model and lipid peroxidation level and significantly increased the level of glutathione peroxides, catalase, and superoxide dismutase activity. The MEJG may possess active constituents such as alkaloids, glycosides, flavonoids, and terpenes, which may play a major role in gastroprotective effect in Wistar rats. Conclusion: The present study provides scientific support for the anti-ulcer activities of extracts of JG and also claimed that antioxidant potential of the extracts. However, substantiates the traditional claims for the usage of this drug in the treatment of gastric ulcer.

}, keywords = {Antioxidant enzymes, anti-ulcer, Aspirin, ethanol, jatropha gossypiifolia, ranitidine, Wistar rats}, doi = {10.4103/0974-8490.178640}, author = {Arumugam Ramamoorthy Vijayakumar and Epison Prabu Daniel and Raju Ilavarasan and S. Venkataraman and S. Vijayakumar} }