@article {406, title = {The optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method}, journal = {Pharmacognosy Research}, volume = {7}, year = {2015}, month = {December 2014}, pages = {57-65}, type = {Original Article}, chapter = {57}, abstract = {

Aim: The aim of this study was to examine and evaluate crucial variables in essential oils extraction process from Lavandula hybrida through static-dynamic and semi-continuous techniques using response surface method. Materials and Methods: Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique. Results: Using response surface method the optimum extraction yield (4.768\%) was obtained via SDS at 108.7 bar, 48.5{\textdegree}C, 120 min (static: 8{\texttimes}15), 24 min (dynamic: 8{\texttimes}3 min) in contrast to the 4.620\% extraction yield for the SC at 111.6 bar, 49.2{\textdegree}C, 14 min (static), 121.1 min (dynamic). Conclusion: The results indicated that a substantial reduction (81.56\%) solvent usage (kg CO2/g oil) is observed in the SDS method versus the conventional SC method.

}, keywords = {Essential oil, lavandin, Lavandula hybrida, Response surface method, Static-dynamic steps, Supercritical carbon dioxide.}, doi = {10.4103/0974-8490.147209}, author = {Hossein Kamali and Noushin Aminimoghadamfarouj and Ebrahim Golmakani and Alireza Nematollahi} }