@article {1332, title = {Quality Standards of Athiyadhi Kashayam - A Polyherbal Classical Siddha Formulation with Potent Anti-Diabetic Ingredients}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {January 2025}, pages = {31-41}, type = {Original Article}, chapter = {31}, abstract = {

Background: Diabetes mellitus is considered a major disease because it is a silent killer associated with many co-morbidities. The recent days{\textquoteright} changes in habits, lifestyle, food habits, stress, etc., have affected good health of people and hence they are seeking traditional medicines like Siddha which are time tested. Athiyadhi Kashayam (AK) is an important Siddha polyherbal formulation containing 5 barks Atthi (Ficus racemosa), Aavarai (Senna auriculata), Sarakkondrai (Cassia fistula), Naaval (Syzygium cumini) and Kadal azhinjil (Salacia oblonga). The compound formulation AK is a combination of antidiabetic ingredients due to which it is a good medicine for diabetes mellitus and co-morbidities. The current study is the first attempt to standardize the formulation as per pharmacopeial standards and to justify the formulation as a potent antidiabetic herbal drug. Materials and Methods: Pharmacognostic, physiochemical and HPTLC studies were carried out as per standard procedures mentioned in Pharmacopoeias. Literature on phytochemistry and pharmacology of each ingredient were compiled to justify the antidiabetic potential of the medicine. Results: Macroscopy, microscopy, powder microscopy, physiochemical analysis and HPTLC was matched with the characters of these ingredients as reported in pharmacopoeias. The earlier reports have revealed the potential phytochemicals in the ingredients revealing its possible benefits for diabetes and related comorbidities. Conclusion: Botanical and chemical standards for quality control of AK have been obtained following standard testing protocol which will give monographic data on identity and quality parameters of this unexplored Siddha medicine. The formula composition from the 5 ingredients with potential antidiabetic properties and managing other comorbidities makes this formula a potent medicine for antidiabetic applications.

}, keywords = {Madhu megam, Monograph, Non-communicable diseases, Quality of life, Standardization}, doi = {10.5530/pres.20251688}, author = {Meenakshi Chandrasekaran and Susikumar Sundharamoorthy and Sunil Kumar Koppala Narayana and Bharath Kumar Govindaraju} } @article {1221, title = {Macro-Microscopic and HPTLC Atlas of Argyreia sericea Dalzell}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {April 2024}, pages = {357-366}, type = {Original Article}, chapter = {357}, abstract = {

Background: Argyreia sericea Dalzell (Convolvulaceae) is a densely hirsute stout climbing shrub found throughout the dry deciduous forests of India. A. sericea is morphologically related to Argyreia nervosa (Burm.f.) Bojer and Argyreia involucrata C.B.Clarke which are used in traditional systems of medicine for treatment of various diseases. As related species look similar in dried form. Objectives: A macro-microscopic and HPTLC study was planned on whole plant parts of A. sericea to analyze key distinguishing characters. Materials and Methods: Standard pharmacopoeial procedures were employed to obtain all the results of the study. Results: Surface characters, odour and taste; transverse section of leaf, stem, root and stomata of epidermal cells, cluster crystal, trichomes, mesophyll tissue, laticiferous content, brownish content, fibres, starch grains, tracheids, fibres tracheids, pitted vessels with scalariform perforation along with pitted, spiral and annular thickening are the unique diagnostic characters observed. Fingerprint profile with unique Rf obtained by HPTLC will aid in correct identification of the species. Conclusion: The findings of the present study will be helpful in identification and differentiation from related species as whole drug or in powder from.

}, keywords = {Bidhara, Controversial drugs, Monograph, Pharmacognosy, Plant anatomy, Standardization.}, doi = {10.5530/pres.16.2.45}, author = {Susikumar Sundharamoorthy and Sunil Kumar Koppala Narayana and Murugammal Shanmugam and Shakila Ramachandran and Elankani Poovan and Dayanand Reddy Gaddam and Ganesan Rethinam} }