Standardization of Madhumukthi Kudineer Chooranum Using Pharmacognostic, Physicochemical and HPTLC Studies

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Abstract
Pharmacognosy Research,2024,16,3,531-539.
Published:June 2024
Type:Original Article
Authors:
Author(s) affiliations:

Rajamanickam Baskar1,2,*, Govindaraju Bharathkumar2, Koppala Narayana Sunil Kumar3, Ramachandran Shakila4, Manekshah Yovas Rajammal5, Sikkal Selvaraaju Selvapriya1, Thangarasu Hema Devi6

1Department of Gunapadam (Pharmacology), Government Siddha Medical College, Chennai, Tamil Nadu, INDIA.

2Department of Siddha, The TN Dr. MGR Medical University, Chennai, Tamil Nadu, INDIA.

3Department of Pharmacognosy, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.

4Department of Chemistry, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.

5State Licencing Authority (Indian Medicine), Chennai, Tamil Nadu, INDIA.

6Arignar Anna Government Hospital of Indian Medicine, Chennai, Tamil Nadu, INDIA.

Abstract:

Background: Siddha system of medicine is considered to be foremost among other systems of medicine. Many medicines are available in traditional systems for all kind of diseases. Most people show their interest towards Siddha medicine for non-communicable diseases especially for diabetes, hypertension, etc., Poly herbal formulations like Avarai kudineer has been authorized for prescription for Madhumegam. Madhumukthi Kudineer Chooranum (MKC) is one such medicine which has been found efficacious in Madhumegam (Diabetes mellitus). The current study is aimed at standardizing MKC employing pharmacognostic and chemical analyses with the aim of developing standards for quality control of this important medicine of Siddha. Materials and Methods: MKC was analyzed for pharmacognostic, physiochemical and HPTLC standards following standard procedures mentioned in Pharmacopoeias. Results: Macroscopy, powder microscopy was matched with the characters of these ingredients as reported in pharmacopoeias. The physicochemical standards were correlated with standards. TLC of MKC showed 10 spots under UV 254 nm, 13 spots under UV 366 nm and after spray with 5% vanillin sulphuric acid solution. Conclusion: The reported results will be supportive for standardization and future studies of MKC.

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Physico-chemical parameters of Madhumukthi Kudineer Chooranum.

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