Evaluation of Haematinic Potential of a Herbomineral Formulation (HMF-TE) in Haloperidol Induced Anaemic Rats

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Abstract
Pharmacognosy Research,2009,1,4,192-196.
DOI:
Published:January 2010
Type:Original Article
Authors:
Author(s) affiliations:

Ashish Trivedi, SH Mishra

Pharmacy Department, Faculty of Tech and Engg., The M.S. University of Baroda, Kalabhavan, Baroda 390002, Gujarat, INDIA.

Abstract:

Iron deficiency anemia is one of the most common nutritional disorders worldwide, especially in India where 87% of pregnant women suffer from anemia and out of these about 10% have severe anemia (H < 80 g/l). In the present study a new modified herbomineral formulation (HMF-TE) containing two natural mineral sources was prepared in laboratory along with different supportive herbs. This formulation was evaluated for its haematinic potential in haloperidol induced anemic rats. The formulation (HMF-TE) exhibited significant haematinic potential by increasing parameters like haematocrit value, hemoglobin concentration, RBC count, MCV, MCH and MCHC.

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HPTLC fingerprint of both formulations (methanol extract) Key: 1= methanol extract of Efiplus caps® 2= methanol extract of HMF-TE AS reagent- Anisaldehyde- sulphuric acid acid reagent.

Keywords