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Year : 2017  |  Volume : 9  |  Issue : 1  |  Page : 74-79

Growth inhibition and morphological alteration of Fusarium sporotrichioides by Mentha piperita essential oil

1 Department of Biochemistry and Nanosciences Discipline, Defence Food Research Laboratory, Mysore, Karnataka, India
2 Department of Food Biotechnology, Defence Food Research Laboratory, Mysore, Karnataka, India

Correspondence Address:
Farhath Khanum
Biochemistry and Nanosciences Discipline, Defence Food Research Laboratory, Mysore, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-8490.199771

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Objective: The aim of this study is to determine the phytochemical composition, antifungal activity of Mentha piperita essential oil (MPE) against Fusarium sporotrichioides. Methods: The phytochemical composition was conducted by gas chromatography mass spectrometry (GC MS) analysis and mycelia growth inhibition was determined by minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC), the morphological characterization was observed by scanning electron microscopy. Finally, the membrane permeability was determined by the release of extracellular constituents, pH, and total lipid content. Result: In GC MS analysis, 22 metabolites were identified such as menthol, l menthone, pulegone, piperitone, caryophyllene, menthol acetate, etc. The antifungal activity against targeted pathogen, with MIC and MFC 500 μg/mL and 1000 μg/mL, respectively. The MPE altered the morphology of F. sporotrichoides hyphae with the loss of cytoplasm content and contorted the mycelia. The increasing concentration of MPE showed increase in membrane permeability of F. sporotrichoides as evidenced by the release of extracellular constituents and pH with the disruption of cell membrane indicating decrease in lipid content of F. sporotrichoides. Conclusion: The observed results showed that MPE exhibited promising new antifungal agent against Fusarium sporotrichioides.

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