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Year : 2015  |  Volume : 7  |  Issue : 1  |  Page : 57-65

The optimization of essential oils supercritical CO 2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method

1 Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd, Iran
2 Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Correspondence Address:
Dr. Alireza Nematollahi
Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-8490.147209

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Aim: The aim of this study was to examine and evaluate crucial variables in essential oils extraction process from Lavandula hybrida through static-dynamic and semi-continuous techniques using response surface method. Materials and Methods: Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique. Results: Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5° C , 120 min (static: 8×15), 24 min (dynamic: 8×3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2° C , 14 min (static), 121.1 min (dynamic). Conclusion: The results indicated that a substantial reduction (81.56%) solvent usage (kg CO 2 /g oil) is observed in the SDS method versus the conventional SC method.

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