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Year : 2009  |  Volume : 1  |  Issue : 5  |  Page : 270-273

Antioxidant activity of Aquilaria malaccensis (thymelaeaceae) leaves

1 Department of Chemical Sciences, Faculty of Science & Technology, Universiti Malaysia Terengganu, Malaysia
2 Institute of Marine Biotechnology, Universiti of Malaysia Terengganu, Malaysia
3 Malaysian Nuclear Agency (MNA), Kajang, Selangor, Malaysia

Correspondence Address:
A.W.N Huda
Department of Chemical Sciences, Faculty of Science & Technology, Universiti Malaysia Terengganu
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Source of Support: None, Conflict of Interest: None

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The phytochemical and antioxidant activity of Aquilaria malaccensis leaves were investigated. The sequential maceration extraction methods utilizing solvents with different polarities namely hexane, ethyl acetate and methanol yielded the corresponding crude extract. The extracts were subjected to preliminary phytochemical screening and revealed the presence of alkaloids, flavanoids, triterpenoids, steroids and saponins. The phytochemical screening suggests that flavanoids present in this species might provide a great value of antioxidant activity. Preliminary screenings of the free radical scavenging activity on the extracts of the plants with 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) were tested and showed positive result. Quarcetine was used as reference standard. The extracts exhibited strong antioxidant activity radical scavenging activity with IC 50 value of 8.0 Χ 10 2 μg/ml, 1.6 Χ 10 2 μg/ml, 1.4 Χ 10 2 μg/ml, 30.0 μg/ml and 3.33 μg/ ml for hexane, DCM, ethyl acetate, methanol and quarcetine respectively.

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