Home | About PR | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Advertise | Contact us |   Login 
Pharmacognosy Magazine
Search Article 
Advanced search 
Year : 2009  |  Volume : 1  |  Issue : 3  |  Page : 102-105

Effect of methyl jasmonate on production of ariltetralin lignans in hairy root cultures of Linum tauricum

Faculty of Pharmacy, Medical University of Sofia, Dunav Str. 2, 1000 Sofia, Bulgaria

Correspondence Address:
Iliana Ionkova
Faculty of Pharmacy, Medical University of Sofia, Dunav Str. 2, 1000 Sofia
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Methyl jasmonate (MeJA) treatment increases the levels of plant secondary metabolites, including ariltetraline lignans, which are considered to be the main active compounds in Linum tauricum. This study was concentrated on the induction of production of ariltetralin lignans in hairy roots cultures of L. tauricum, transformed by Agrobacterium rhyzogenes, ATCC 15834 by exposing them to different concentrations (50-200 microM) of methyl jasmonate (MeJA) during the culture period. The content of 4'-demethyl-6-methoxypodo-phylotoxin (4'-DM­6MPTOX) and 6-methoxypodophyllotoxin (MPTOX), the main constituents in hairy roots of L. tauricum increased about 1.2 folds by elicitation of MeJA, however, the fresh weight, dry weight and growth ratio was inhibited by increasing MeJA concentrations. The highest total lignans yield was obtained with 150 microM MeJA treatment. These results suggest that MeJA elicitation is beneficial for lignan accumulation in the hairy roots cultures of L. tauricum.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded63    
    Comments [Add]    

Recommend this journal